Corydalis yanhusuo
| Corydalis yanhusuo | |
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| Species: | C. yanhusuo
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| Corydalis yanhusuo | |
Corydalis yanhusuo is a species of genus Corydalis. Research has indicated that the alkaloid dehydrocorybulbine (DHCB), extracted from the roots of the plant, can be helpful in reducing neuropathic pain.[1][2] Tetrahydropalmatine is a major constituent alkaloid which also has analgesic activity.[2]
Corydalis yanhusuo also contains the alkaloids glaucine[3][4] and palmatine.[5] It also contains the acetylcholinesterase inhibitor corydaline.[6]
N-methyltetrahydroprotoberberines with κ-opioid receptor agonist activity have been isolated from C. yanhusuo.[7]
References
- ^ Chinese herbal compound relieves inflammatory and neuropathic pain
- ^ a b A Novel Analgesic Isolated from a Traditional Chinese Medicine. Current Biology. Volume 24, Issue 2, p117–123, 20 January 2014
- ^ Xu, XH; Yu, GD; Wang, ZT (2004). "Resource investigation and quality evaluation on wild Corydalis yanhusuo". Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 29 (5): 399–401. PMID 15706885.
- ^ Morteza-Semnani, K; Amin, G; Shidfar, MR; Hadizadeh, H; Shafiee, A (2003). "Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum". Fitoterapia. 74 (5): 493–6. doi:10.1016/s0367-326x(03)00113-8. PMID 12837370.
- ^ Wang YM, Zhao LB, Lin SL, Dong SS, An DK (1989). "[Determination of berberine and palmatine in cortex phellodendron and Chinese patent medicines by HPLC]". Yao Xue Xue Bao = Acta Pharmaceutica Sinica (in Chinese). 24 (4): 275–9. PMID 2816389.
- ^ Xiao, Hai-Tao; Peng, Jiao; Liang, Yan; Yang, Jie; Bai, Xue; Hao, Xiao-Yan; Yang, Fu-Mei; Sun, Qian-Yun (September 2011). "Acetylcholinesterase inhibitors from Corydalis yanhusuo". Natural Product Research. 25 (15). Taylor and Francis: 1418–1422. doi:10.1080/14786410802496911. ISSN 1478-6419. PMID 20234973. Retrieved September 8, 2013.
- ^ Yan Zhang; Chaoran Wang; Zhimou Guo; Xiuli Zhang; Zhiwei Wang; Xinmiao Liang; Olivier Civelli (2014). "Discovery of N-methyltetrahydroprotoberberines with κ-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography". Journal of Ethnopharmacology. 155 (3): 1597–1602. doi:10.1016/j.jep.2014.07.057. PMID 25107388.
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