Jenji L. Kohan is the daughter of Rhea and Buz Kohan. Her father is an Emmy Award-winning television writer, and her brother David Kohan is an Emmy Award-winning television producer. Kohan has twin brothers, David Kohan and Jono.
Early in Kohan's career, she worked for her brother on Will & Grace. She has discussed the differences between her and her brother's career saying, “David took the big, commercial, funny route; I was always a little darker personally, and not terrific within the system. I had to make my own way.”