Pulegone
| Pulegone[1] | |
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(R)-5-Methyl-2-(1-methylethylidine)cyclohexanone |
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Other names
p-Menth-4(8)-en-3-one; |
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| Identifiers | |
| CAS number | 89-82-7  |
| PubChem | 442495 |
| ChemSpider | 390923 |
| UNII | 4LF2673R3G |
| ChEBI | CHEBI:35596 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C10H16O |
| Molar mass | 152.23 g/mol |
| Appearance | Colorless oil |
| Density | 0.9346 g/cm3 |
| Boiling point |
224 °C, 497 K, 435 °F |
| Solubility in water | Insoluble |
| Solubility in Ethanol Ether Chloroform |
Miscible |
| Hazards | |
| MSDS | MSDS[2] |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Pulegone is a naturally occurring organic compound obtained from the essential oils of a variety of plants such as Nepeta cataria (catnip), Mentha piperita, and pennyroyal.[3][4] It is classified as a monoterpene.
Pulegone is a clear colorless oily liquid and has a pleasant odor similar to pennyroyal, peppermint and camphor. It is used in flavoring agents, in perfumery, and in aromatherapy.
Contents |
[edit] Toxicology
It was reported that the chemical is toxic to rats if a large quantity is consumed.[5] Asekun et al. found that the chemical content of Mentha longifolia L was decreased by the treatments at high temperatures, suggesting that the herb should be oven dried or thoroughly cooked before consumption.[6]
[edit] Plants that contain the chemical
[edit] Notes and references
- ^ Merck Index, 11th Edition, 7955.
- ^ Universiti Malaysia Pahang. "Safety data sheet". http://notes.ump.edu.my/fkksa/FKKSA/Archive/Technical%20Unit/Warehouse%20Unit/Chemical/MSDS/MERCK_EN/8186/818665.pdf. Retrieved 8 June 2009.
- ^ Grundschober, F. (1979) Literature review of pulegone. Perfum. Flavorist, 4, 15–17.
- ^ Sullivan, J.B., Rumack, B.H., Thomas, H., Peterson, R.G. & Brysch, P. (1979) Pennyroyal oil poisoning and hepatotoxicity. J. Am. Med. Assoc., 242, 2873–2874.
- ^ Thorup, I. et al.; Würtzen, G; Carstensen, J; Olsen, P (1983). "Short term toxicity study in rats dosed with pulegone and menthol". Toxicology Letters 19 (3): 207–210. doi:10.1016/0378-4274(83)90120-0. PMID 6658833.
- ^ a b Asekun, O.T. et al.; Grierson, D; Afolayan, A (2006). "Effects of drying methods on the quality and quantity of the essential oil of Mentha longifolia L. subsp. Capensis". Food Chemistry 101 (3): 995–998. doi:10.1016/j.foodchem.2006.02.052.
- ^ Gordon, W. Perry et al.; Valerie Howland (1982). "Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituent terpenes in the mouse". Toxicology and Applied Pharmacology 65 (3): 413–424. doi:10.1016/0041-008X(82)90387-8. PMID 7157374.
- ^ Farley, Derek R.; Valerie Howland (2006). "The natural variation of the pulegone content in various oils of peppermint". Journal of the Science of Food and Agriculture 31 (11): 1143–1151. doi:10.1002/jsfa.2740311104.
