Superior orbital fissure
|Superior orbital fissure|
Orbit seen from the front, with bones labeled in different colors, and superior orbital fissure at center as an "hour-glass" formation.
|Latin||fissura orbitalis superior|
|Anatomical terms of bone|
Structures passing through
A number of important anatomical structures pass through the fissure, and these can be damaged in orbital trauma, particularly blowout fractures through the floor of the orbit into the maxillary sinus. These structures are:
- superior and inferior divisions of oculomotor nerve (III)
- trochlear nerve (IV)
- lacrimal, frontal and nasociliary branches of ophthalmic (V1).
- abducens nerve (VI)
- superior and inferior divisions of ophthalmic vein. Inferior division also passes through the inferior orbital fissure.
- sympathetic fibers from cavernous plexus
These include nonvisual sensory messages, such as pain, or motor nerves. They also serve as vascular connections. 
The nerves passing through the fissure can be remembered with the mnemonic, "Live Frankly To See Absolutely No Insult" - for Lacrimal, Frontal, Trochlear, Superior Division of Oculomotor, Abducens, Nasociliary and Inferior Division of Oculomotor nerve. 
It is divided into 3 parts from lateral to medial: Lateral Part transmits: lacrimal nerve, frontal nerve, trochlear nerve, meningeal branch of lacrimal artery, anastomotic branch of middle meningeal artery which anastomoses with recurrent branch of the lacrimal artery Middle Part transmits: Upper and lower divisions of the oculomotor nerve, nasociliary nerve between the two divisions of oculomotor nerve and abducent nerve Medial Part transmits: Superior ophthalmic vein and sympathetic nerves from the plexus around internal carotid artery
The abducens nerve is most likely to show signs of damage first, with the most common complaints retro-orbital pain and the involvement of cranial nerves III, IV, V1, and VI without other neurological signs or symptoms. This presentation indicates either compression of structures in the superior orbital fissure or the cavernous sinus.
Superior orbital fissure syndrome
Superior orbital fissure syndrome, also known as Rochon-Duvigneaud's syndrome,  is a neurological disorder that results if the superior orbital fissure is fractured. Involvement of the cranial nerves that pass through the superior orbital fissure may lead to diplopia, paralysis of extraocular motions, exophthalmos, and ptosis. Blindness or loss of vision indicates involvement of the orbital apex, which is more serious, requiring urgent surgical intervention. Typically, if blindness is present with superior orbital syndrome, it is called orbital apex syndrome.
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- synd/3387 at Who Named It?
- A. Rochon-Duvigneaud. Quelques cas de paralysie de tous les nerfs orbitaires (ophthalmoplegie totale avec amaurosse en anesthésie dans le domaine de l’ophthalmique d’origine syphilitique). Archives d'ophthalmologie, Paris, 1896, 16: 746-760.
- SUNY Figs 22:02-04
- lesson3 at The Anatomy Lesson by Wesley Norman (Georgetown University) (orbitforamina) (#2)
- cranialnerves at The Anatomy Lesson by Wesley Norman (Georgetown University) (V)
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- Anatomy diagram: 34257.000-2 at Roche Lexicon - illustrated navigator, Elsevier