User:Madhero88/House

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Season 1[edit]


Episode # Title Director Writer(s) Original airdate Final diagnosis


1 (1-01)"Pilot  Done"Bryan SingerDavid ShoreNovember 16, 2004Neurocysticercosis
Rebecca Adler (Robin Tunney), a 29-year old kindergarden teacher, becomes dysphasic and collapses in her classroom. Dr. Gregory House initially refuses the case until Dr. James Wilson tells him that Rebecca is Wilson's cousin. When Dr. Lisa Cuddy tries to make House fulfill his clinical duties, he refuses but is forced to do them when his authorization to the MRI is revoked. He diagnoses Rebecca with cerebral vasculitis and her condition improves with treatment. To find the source of Rebecca's seizures, House convinces Dr. Eric Foreman to break into Rebecca's house. At the hospital, Rebecca suddenly loses her vision and suffers another seizure. Foreman discovers ham at Rebecca's house, revealing both Wilson's lie (Wilson is Jewish) and the cause of the seizure—tapeworms. When Rebecca refuses treatment, House persuades her otherwise by proving her condition with a non-invasive X-ray suggested by Dr. Robert Chase.
2 (1-02)"Paternity  Done"Peter O'FallonLawrence KaplowNovember 23, 2004Subacute sclerosing panencephalitis
A 16-year-old high school student, Dan (Scott Mechlowicz), starts suffering night terrors and frequent hallucinations after playing lacrosse at school. The parents take him to Dr. House after receiving a letter that Cameron sent in House's name and House starts a bet on whether they are his biological parents. After Dan exhibits more symptoms, including a myoclonic twitch and a blocked blood vessel, House diagnoses Dan. Dan suffers from an auditory hallucination during a procedure, however, ruling out House's diagnosis. Using the coffee cups from the parents, House does a paternity test and discovers that neither parent is biologically related to Dan. When he remembers a case he had earlier, when the mother of a baby did not want vaccination for her child, he theorizes that Dan is suffering from a measles virus contracted during his childhood. House confirms his diagnosis with a retinal biopsy and successfully cures Dan.
3 (1-03)"Occam's Razor  Done"Bryan SingerDavid ShoreNovember 30, 2004Colchicine poisoning
A college student named Brandon (Kevin Zegers) collapses after having sex with his fiancée. His symptoms seem too numerous to be explained by just one disease. Foreman and House each suggest different diagnoses and argue that his own respective theory better conforms to Occam's Razor. But when Brandon's white blood cell count drops, proving both doctors wrong. At the clinic pharmacy, House theorizes that Brandon was accidentally given colchicine instead of cough medicine, which explains all of his symptoms aside from his cough. House gives Brandon the cure, and he immediately begins to recover, yet the doctors are unable to find the source of the colchicine. However, when Brandon comments that his old cough medicine did not have letters on it like his current pills, House discovers colchicine pills that look similar to cough medicine, revealing the source and confirming House's diagnosis.
4 (1-04)"Maternity  Done"Newton Thomas SigelPeter BlakeDecember 7, 2004Echovirus 11
After overhearing a conversation about a sick baby, House investigates the maternity ward and predicts an epidemic. After realizing the severity of the disease, Cuddy quarantines the maternity ward. In an effort to discover the source of the epidemic, House begins treating the children. However, when the kidneys of two of the children shut down, House is forced to test which drug caused the failure, causing one of the babies to die. Following an autopsy, the team discovers the presence of Echovirus 11, CMV, and Parvovirus B19 antibodies. They test the mothers and decide the cause of the epidemic is the Echovirus. Using an experimental anti-virus, they cure the babies. House, determined to find the entry point of the virus, finds an elderly hospital volunteer coughing and wiping her nose as she pushes around a cart of baby toys and blankets and makes the connection.
5 (1-05)"Damned If You Do  Done"Greg YaitanesSara B. CooperDecember 14, 2004Copper allergy
Sister Augustine (Elizabeth Mitchell), a nun, arrives at the hospital with her hands covered in rash, but House quickly dismisses the case after treating with antihistamines, suspecting an allergic reaction to dish soap. However, she has an asthma attack and House administers epinephrine, causing her heartbeat to increase. House's team suspects that House made a mistake, but when they try to find the source of her problems, she suffers convulsions and a rash appears on her leg. Cuddy pulls House off of the case when she hears of House's methodology. An investigation of the convent reveals figwort tea, which caused the reaction with the epinephrine, but the Sister's original symptoms are still unexplained. When she is placed in a hypoallergenic room and still has an allergic reaction, but her shouts that she has God inside her allow House to find a copper IUD inside Sister Augustine's uterus, which she is allergic to. The device is surgically removed and she fully recovers.
6 (1-06)"The Socratic Method  Done"Peter MedakJohn MankiewiczDecember 21, 2004Vitamin K deficiency, hepatocellular carcinoma, and Wilson's disease
A mother, Lucille Palmeiro, collapses after a blood clot travels from her leg to her heart. After arriving in the hospital, she begins to vomit blood, causing House to expect a Vitamin K deficiency. House's team discover unused Ampicillin and frozen microwave burgers, supporting House's diagnosis. An ultrasound of Lucille's liver reveals cirrhosis and a cancerous tumor. House treats the tumor with ethanol, but is unable to explain the cirrhosis. However, Lucille, in a decision House claims to be inconsistent with her schizophrenia, calls Social Services to take her son. House realizes that Wilson's disease explains the cirrhosis and an eye exam shows copper-colored rings around her corneas. Lucille receives treatment, is healed, and reunites with her son.
7 (1-07)"Fidelity  Done"Bryan SpicerThomas L. MoranDecember 28, 2004Human African trypanosomiasis
Two men are out jogging – one of them (guest star Dominic Purcell) returns home to his bedridden wife, who lashes out at him. Believing there is something wrong, she is sent to Princeton-Plainsboro, and when all the treatments fail, House concludes she has African sleeping sickness. However, neither the wife nor her husband have ever been to Africa. The woman will die without proper treatment, but neither one will also admit to having an affair.
8 (1-08)"Poison  Done"Guy FerlandMatt WittenJanuary 25, 2005Phosmet poisoning
House and his team investigate the mysterious poisoning of high-school student Matt Davis (guest star John Patrick Amedori), until another teen is brought in with all of the same symptoms but almost nothing else in common with Matt.
9 (1-09)"DNR  Done"Frederick King KellerDavid FosterFebruary 1, 2005Arteriovenous malformation
A legendary jazz musician named John Henry Giles (Harry J. Lennix) collapses during a recording session. House and his team are told to only treat him for his pneumonia, and not his partial paralysis. John Henry files a Do Not Resuscitate (DNR) order, and chokes during a routine exam. House ignores the DNR order and ends up in court. All the doctors, including John Henry's own doctor, except for House believe that he has ALS. Cameron notices a blood clot, which is removed with surgery. John Henry recovers, and an MRI shows that he had suffered from Arteriovenous malformation. Meanwhile, Foreman receives a lucrative job offer from John Henry's doctor, but turns it down.
10 (1-10)"Histories  Done"Dan AttiasJoel ThompsonFebruary 8, 2005Tuberculoma and rabies
Dr. Foreman believes an uncooperative homeless woman is faking seizures to get a meal ticket at the hospital. But her situation strikes a chord with Dr. Wilson and he resolves to keep her from falling between the cracks. Meanwhile, House has an audience of two medical students who are learning how to conduct medical histories.
11 (1-11)"Detox  Done"Nelson McCormickLawrence Kaplow and Thomas L. MoranFebruary 15, 2005Naphthalene poisoning
While trying to figure out why a young patient will not stop bleeding after a car wreck, House accepts Cuddy's challenge and goes off Vicodin for a week in exchange for no clinic duty for a month. As House's withdrawal symptoms become severe, his methodology for his patient are more harsh and risky, and Foreman and Cameron are afraid he may not be thinking clearly enough to save the patient's life.
12 (1-12)"Sports Medicine  Done"Keith GordonJohn Mankiewicz and David ShoreFebruary 22, 2005Cadmium poisoning
A severely broken arm reveals a bizarre case of bone loss and ends the comeback plans of major league pitcher Hank Wiggen. House suspects Hank – with a history of drug abuse – is lying about using steroids, as his condition worsens. When Hank's kidneys start to fail, his wife offers to donate hers, but she will have to abort her early pregnancy, something Hank does not want. Meanwhile, Foreman dates a pharmaceutical representative and House is stuck with an extra ticket to a monster truck rally.
13 (1-13)"Cursed  Done"Daniel SackheimMatt Witten and Peter BlakeMarch 1, 2005Anthrax and leprosy
After consulting a Ouija board, a young boy believes he is going to die, and is sent to Princeton-Plainsboro after suffering from pneumonia. Dr. Chase's estranged father (guest star Patrick Bauchau) comes to the hospital and helps House diagnose the kid.
14 (1-14)"Control  Done"Randy ZiskLawrence KaplowMarch 15, 2005Congestive heart failure onset by bulimia and regular use of ipecac
Billionaire entrepreneur Edward Vogler donates $100 million to Princeton-Plainsboro and becomes the new Chairman of the Board. Vogler intends to turn the clinic into a profitable venue for his biotech venture and plans to eliminate House's financially draining department. Meanwhile, a businesswoman has it all – perfect life, perfect body, perfect job – until she finds herself inexplicably paralyzed. When he diagnoses her condition, House must risk his job and his medical license to save her.
15 (1-15)"Mob Rules  Done"Tim HunterDavid Foster and John MankiewiczMarch 22, 2005Ornithine transcarbamylase deficiency
House is placed under a court order to determine what is ailing a mobster due for federal testimony and the Witness Protection Program. The witness's brother, a lawyer, works against the team and the testimony when his brother is diagnosed with Hepatitis C. Cuddy continues to battle Vogler over House's importance to the hospital.
16 (1-16)"Heavy  Done"Fred GerberThomas L. MoranMarch 29, 2005Cushing's Disease
House and his team investigate an overweight ten-year-old girl who has a heart attack. Adding to his stress, Vogler demands House get rid of a member of his team.
17 (1-17)"Role Model  Done"Peter O'FallonMatt WittenApril 12, 2005Delayed-onset CVID secondary to phenytoin-mediated Epstein-Barr virus infection.
A popular U.S. senator and presidential candidate succumbs to illness at a fundraiser and Vogler assigns House to his case. He also tells House he can keep his whole team if he endorses Vogler's pharmaceutical company. The Senator's initial diagnosis seems to point to AIDS, but House digs deeper for another answer. Meanwhile, he also handles a case of a woman who apparently gets pregnant without having sex. Cameron visits House and tells him that she is leaving her job.
18 (1-18)"Babies & Bathwater  Done"Bill JohnsonPeter Blake and David Shore (teleplay)
Peter Blake (story)
April 19, 2005LEMS secondary to Small cell lung carcinoma
A pregnant woman arrives at the hospital with brain and kidney problems and House must contend with her condition and Vogler's eagerness to see the doctor removed by using the board members. The patient and her husband must decide between her life and their unborn child's, after the team discovers small cell lung cancer.
19 (1-19)"Kids  Done"Deran SarafianThomas L. Moran and Lawrence KaplowMay 3, 2005Thrombotic thrombocytopenic purpura secondary to pregnancy
House fights off a meningitis outbreak and Cuddy gives his team an hour to produce results after he singles out a young patient who does not quite fit the criteria. House tries to get Cameron to return in the wake of Vogler's departure, but she demands House tell her why he really wants her back.
20 (1-20)"Love Hurts  Done"Bryan SpicerSara B. CooperMay 10, 2005Fulminating osteomyelitis
The teaching hospital buzzes with rumors of House's upcoming date with Cameron. After House is harsh to an awaiting clinic patient (guest star John Cho), the man develops a mysterious stroke. At the same time, House also deals with an elderly couple whose overactive sex life causes them problems.
21 (1-21)"Three Stories  Done"Paris BarclayDavid ShoreMay 17, 2005
House receives a visit from an ex-girlfriend, Stacy Warner, who seeks his help for her husband. Cuddy forces House to give a lecture to medical students on diagnosing patients and presents three scenarios, each with different reasons for their leg pain (with guest star Carmen Electra).
22 (1-22)"Honeymoon  Done"Frederick King KellerLawrence Kaplow and John MankiewiczMay 24, 2005Acute intermittent porphyria
House diagnoses Mark, Stacy Warner's husband. Although the tests do not indicate a condition and Mark claims to be fine outside of stomach pain, it appears his brain is dying. House finds abdominal epilepsy, but cannot detect any memory loss. After Mark begins developing paralysis, House decides to treat him for Guillain-Barré syndrome. After confiding in Stacy that he still has feelings for her, House realizes that Mark had experienced delusions, and actually suffered from acute intermittent porphyria (AIP). With support from Stacy, but not from his team, House gives Mark a dangerous drug cocktail to confirm that he really has AIP. Cuddy decides to hire Stacy as the hospital's lawyer.

Season 2[edit]

Episode # Title Director Writer(s) Original airdate Final diagnosis
23 (2-01)"Acceptance  Done"Dan AttiasRussel Friend & Garrett LernerSeptember 13, 2005
House is brought in for a consult on a Death Row inmate (guest star LL Cool J) with mysterious symptoms. Cameron feels the hospital's resources are better used elsewhere for a young cancer patient. House and Stacy try to establish a good work relationship, especially after he lies to her to secure the transfer of the inmate to the hospital.
24 (2-02)"Autopsy  Done"Deran SarafianLawrence KaplowSeptember 20, 2005Thrombosis
A nine-year-old cancer patient is brought before House after she experiences hallucinations. House figures out a way to help her, but it will involve serious risk. They discover she has a tumor on her heart, but when it turns out to be benign, the team decides a clot may be navigating her body.
25 (2-03)"Humpty Dumpty  Done"Dan AttiasMatt WittenSeptember 27, 2005Endocarditis due to psittacosis
Cuddy feels responsible when her handyman falls off her roof then exhibits weird symptoms. House's team amputates the handyman's hand to prevent the spread of infection, but when the other hand starts showing similar signs, they must seek out the source before it kills the patient.
26 (2-04)"TB or Not TB  Done"Peter O'FallonDavid FosterNovember 1, 2005Nesidioblastoma and tuberculosis
A famous doctor (guest star Ron Livingston) falls ill when working in Africa, and is sent to House for treatment. Tensions mount when House refuses to believe he has tuberculosis, but everyone else believes so.
27 (2-05)"Daddy's Boy  Done"Greg YaitanesThomas L. MoranNovember 8, 2005Cavernous angioma and radiation poisoning
A student who just graduated from Princeton experiences severe spasms at a graduation party. Meanwhile, House's parents drop by but he is reluctant to see them, igniting curiosity among the hospital staff.
28 (2-06)"Spin  Done"Fred GerberSara HessNovember 15, 2005Air embolism, pure red cell aplasia, thymoma, and myasthenia gravis
A famous cyclist is brought to Princeton-Plainsboro after collapsing during a race. He is surprisingly honest about several illegal medications and techniques he applies to himself, but his sickness is not caused by any of these.
29 (2-07)"Hunting  Done"Gloria MuzioLiz FriedmanNovember 22, 2005Echinococcosis
House is confronted by Kalvin, a flamboyant homosexual man who demands treatment when other doctors diagnose him with AIDS, something he admits he does have. House begins making moves on Stacy using sensitive information on her relationship with Mark.
30 (2-08)"The Mistake  Done"David SemelPeter BlakeNovember 29, 2005Behcet's disease, then hepatitis C and hepatocellular carcinoma from a liver transplant
A lawsuit is brought against Chase and House for the death of a mother who comes in with stomach pain. A disciplinary committee convenes to determine whether either of them is at fault.
31 (2-09)"Deception  Done"Deran SarafianMichael R. PerryDecember 13, 2005Clostridium perfringens and Munchausen syndrome
Anica (guest star Cynthia Nixon), is at a OTB parlor where House observes her have a seizure. She is admitted to the hospital but Cameron wants her to be discharged when they discover she has Munchausen syndrome, however, House believes she has an underlying condition.
32 (2-10)"Failure to Communicate  Done"Jace AlexanderDoris EganJanuary 10, 2006Cerebral malaria
Whilst House and Stacy are in Baltimore, a famed journalist (guest star Michael O'Keefe) collapses in his magazine company's office. While he acts nonchalantly after getting up, it becomes clear from his word-salad-inflected speech that he is suffering from aphasia.
33 (2-11)"Need to Know  Done"David SemelPamela DavisFebruary 7, 2006Ritalin use and hepatocellular adenoma
Cameron worries about the potential results of her HIV test and House basks in the afterglow of his kiss with Stacy, but Wilson tells him to keep a level head about things. House must dig through the life and lies of a busy housewife to find the true reason why she is showing signs of physical and mental degeneration.
34 (2-12)"Distractions  Done"Dan AttiasLawrence KaplowFebruary 14, 2006Serotonin syndrome
The team struggles to diagnose a teen suffering from spasms when severe burns following an accident make most of their usual diagnostic tests impossible. Meanwhile, House exacts revenge on a doctor who turned him in for cheating in medical school.
35 (2-13)"Skin Deep"Jim HaymanRussel Friend, Garrett Lerner & David Shore (teleplay)
Russel Friend & Garrett Lerner (story)
February 20, 2006Androgen insensitivity syndrome and testicular cancer
House treats a teenage supermodel who gets into a catfight on the catwalk and then passes out. When her tox-screen shows heroin, she is treated for addiction; unfortunately, her symptoms continue after she is weaned off the drugs. Meanwhile, House fights off increasingly bad leg pain.
36 (2-14)"Sex Kills"David SemelMatt WittenMarch 7, 2006
House treats a man who unknowingly has a seizure and is in need of a new heart. When the transplant committee votes "no," House tries to get one from a dead woman whose organs have also been rejected by the committee.
37 (2-15)"Clueless"Deran SarafianThomas L. MoranMarch 28, 2006Gold sodium thiomalate poisoning
When a man cannot breathe during sexual role playing with his wife, House questions the motives behind their marriage; Wilson's presence in his house begins to take a toll on him.
38 (2-16)"Safe"Félix Enríquez AlcaláPeter BlakeApril 4, 2006Tick paralysis
Melinda (guest star Michelle Trachtenberg), a troubled teenager who is immuno-compromised as a result of medications she must take after a heart transplant, has a severe allergic reaction and goes into shock when her boyfriend visits her. Meanwhile, House and Wilson continue to work out the problems in their new living arrangement.
39 (2-17)"All In"Fred GerberDavid FosterApril 11, 2006Erdheim-Chester disease
The hospital is hosting an oncology benefit poker tournament when a six year-old boy is brought in exhibiting symptoms identical to those of a patient House had twelve years ago. House is convinced the boy's case is identical and he can predict the course of the young patient's illness, which ended in the first patient's death.
40 (2-18)"Sleeping Dogs Lie"Greg YaitanesSara HessApril 18, 2006Bubonic plague
A young woman's health becomes a question of ethics when she is unable to sleep for ten days. It is not until House discovers she will need a liver transplant that he also uncovers some vital information about her and her partner Max. Meanwhile, Cameron accuses Foreman of plagiarism when an article he authors appears remarkably similar to one of hers.
41 (2-19)"House vs. God"John F. ShowalterDoris EganApril 25, 2006Tuberous sclerosis and herpes encephalitis
House wants to call a 15-year-old faith healer's bluff, but when the boy is admitted into the hospital he seemingly causes a cancer patient's condition to go into remission. After being diagnosed, the boy refuses brain surgery, but when his condition worsens, House and his staff have to make a decision.
42 (2-20)"Euphoria, Part 1"Deran SarafianMatthew V. LewisMay 2, 2006Secondary legionellosis but no final diagnosis
House is trying to cure a crooked cop who acts turbulent and laughs uncontrollably, but he and his team are unable to determine the cause. When Foreman starts showing similar symptoms, the situation gets far worse than anybody expected.
43 (2-21)"Euphoria, Part 2"Deran SarafianRussel Friend & Garrett Lerner & David ShoreMay 3, 2006Induced legionellosis and primary amoebic meningoencephalitis due to infection by Naegleria fowleri
With the police officer dead and fearing for his life, Foreman contacts his father who rushes to his son's side. Meanwhile, House and the rest of the team are still trying to do everything they can to help Foreman.
44 (2-22)"Forever"Daniel SackheimLiz FriedmanMay 9, 2006Pellagra, coeliac disease and MALT lymphoma
On his way out the door, a man vomits and decides to stay home from work, only to find his wife in the bathtub having a seizure and their newborn infant drowning.
45 (2-23)"Who's Your Daddy?"Martha MitchellJohn Mankiewicz & Lawrence Kaplow (teleplay)
Charles M. Duncan & John Mankiewicz (story)
May 16, 2006Haemochromatosis and zygomycosis
A 16 year-old Hurricane Katrina victim suffering from horrifying hallucinations is brought to House by a former bandmate who recently discovered the girl is his daughter. Although House fears his friend is being scammed, he takes the case. As he works his way through the girl's lies in order to diagnose and treat her, he is forced to tell a few lies of his own.
46 (2-24)"No Reason"David ShoreDavid Shore (teleplay)
Lawrence Kaplow & David Shore (story)
May 23, 2006No diagnosis (hallucination by House)
When House and his team are working on the diagnosis of a man with a swollen tongue, the husband of a former patient walks into House's office and shoots him. House continues to treat his patient from his ICU bed with the shooter (guest star Elias Koteas), who is shot by hospital security and handcuffed to his bed, as his roommate. When the after effects of the shooting begin to impact House, he starts to question his own ability to diagnose properly. As his patient's body deteriorates, House struggles through self-doubt and must trust his team to find a way to solve the case.

Season 3[edit]

Episode # Title Director Writer(s) Original airdate Final diagnosis
47 (3-01)"Meaning"Deran SarafianLawrence Kaplow & David Shore (teleplay)
Russel Friend, Garrett Lerner, Lawrence Kaplow & David Shore (story)
September 5, 2006 (2006-09-05)
House has recovered from his gunshot wounds and is back at work, taking on two cases simultaneously: Richard, paralyzed after brain cancer surgery eight years ago, who drove himself on his motorized wheelchair headfirst into a swimming pool, and Caren, a young woman paralyzed from the neck down after a yoga session. As House begins to diagnose and treat them, the team notices a distinct change in his attitude toward his patients.
48 (3-02)"Cane and Able"Daniel SackheimRussel Friend & Garrett Lerner (teleplay)
Russel Friend, Garrett Lerner, Lawrence Kaplow & David Shore (story)
September 12, 2006 (2006-09-12)Chimerism
Seven year-old Clancy is admitted to the hospital with rectal bleeding, claiming alien abduction. The team runs tests, but when they get different results from the same tests, in addition to finding a metal object in his neck, they are forced to give Clancy's testimony a little more credence. Amidst this, Cuddy and Wilson decide not to tell House the truth about his last case, thinking he will learn some humility, while Cameron is outraged at their actions. When a frustrated House gives up on the boy, Cuddy is forced to re-think her decision to hold back the truth.
49 (3-03)"Informed Consent"Laura InnesDavid FosterSeptember 19, 2006 (2006-09-19)Congestive heart failure secondary to senile cardiac amyloidosis
House's new patient is Ezra Powell (guest star Joel Grey), a renowned medical research pioneer who collapses in his lab. House puts Ezra through diagnostic rigors, but the team is unable to come up with a conclusive diagnosis and Ezra's health continues to deteriorate. Ezra ultimately demands the team help him end his life, but each member has divergent opinions on the morality of helping Ezra die, especially since the possibility of a cure is still in question. Meanwhile, the teenage daughter of a clinic patient has developed a disturbing crush on House.
50 (3-04)"Lines in the Sand"Newton Thomas SigelDavid HoseltonSeptember 26, 2006 (2006-09-26)Baylisascaris (Adam) Coccidioidomycosis (Ali)
House takes the case of Adam, a 10 year-old severely autistic boy, who screams loudly for no apparent reason. Cuddy makes a minor change to House's office and he refuses to use it until it is returned to its original state; thus, he finds himself wandering the hospital in need of a temporary office. Meanwhile, the teenage clinic patient still has a crush on House and is becoming a nuisance.
51 (3-05)"Fools for Love"David PlattPeter BlakeOctober 31, 2006 (2006-10-31)Hereditary angioedema
House takes the case of a young woman who is rushed to the hospital with problems breathing and severe stomach pain, after she and her husband are robbed. But when her husband collapses, the team believes the couple's illnesses are related. Meanwhile, clinic patient Michael Tritter causes problems for House.
52 (3-06)"Que Será Será"Deran SarafianThomas L. MoranNovember 7, 2006 (2006-11-07)Small cell lung carcinoma
A morbidly obese man is found in a coma after a fire accident and is admitted to Princeton-Plainsboro. Upon waking up, he demands to be discharged, refusing to be tested for any disease possibly caused by his weight.
53 (3-07)"Son of Coma Guy"Dan AttiasDoris EganNovember 14, 2006 (2006-11-14)MERRF syndrome
House decides to awaken a comatose patient so he can question the man regarding the family history of his son, who may have a genetic condition, and the father is the only living relative. Meanwhile, Wilson confronts House about the stolen prescription as Tritter approaches Cameron, Chase, and Foreman in an attempt to divide the team and reveal their loyalties.
54 (3-08)"Whac-A-Mole"Daniel SackheimPamela DavisNovember 21, 2006 (2006-11-21)Chronic granulomatous disease
House's newest patient is 18 year-old Jack, brought to the hospital after experiencing a heart attack and massive vomiting. Jack has been the sole parent to his younger brother and sister since their parents died. After a brief review of his file, House thinks he has got the diagnosis, seals it in an envelope and turns the process into a game, challenging Cameron, Foreman and Chase to figure it out on their own. Meanwhile, in an attempt to extract a confession, Tritter makes it impossible for Wilson to practice medicine, driving a wedge between the two friends.
55 (3-09)"Finding Judas"Deran SarafianSara HessNovember 28, 2006 (2006-11-28)Erythropoietic protoporphyria
House and the team take on the case of Alice, a young girl with pancreatitis. Since her divorced parents cannot agree on how to proceed with her treatment and will not let House bully them into making a decision, House's only option is to take them to court and let a judge rule on the matter. Meanwhile, House's reduced access to Vicodin is beginning to take its toll and he asks Cuddy for more, but instead of writing a prescription, she strictly rations his pills.
56 (3-10)"Merry Little Christmas"Tony ToLiz FriedmanDecember 12, 2006 (2006-12-12)Langerhans cell histiocytosis
It is Christmas at Princeton-Plainsboro and Wilson has a present for House: he and Detective Tritter have struck a deal and House has three days to accept it. Cuddy receives a patient afflicted with dwarfism, who has a variety of symptoms and is recovering from a recently collapsed lung. Cuddy is eventually forced to make a difficult and potentially life-threatening choice between her patient and House's well-being.
57 (3-11)"Words and Deeds"Daniel SackheimLeonard DickJanuary 9, 2007 (2007-01-09)Spinal meningioma
House is forced to respond in court to the criminal charges against him regarding illegal possession of narcotics, and the judge sets a date for a preliminary hearing. Cuddy insists that House apologize to Tritter; meanwhile, the most recent case at the hospital is a firefighter suffering from disorientation and extremely high body temperatures. Because of misinterpreted information, the firefighter is eventually forced to make a decision to undergo a radical brain treatment which will have a serious effect on his life.
58 (3-12)"One Day, One Room"Juan J. CampanellaDavid ShoreJanuary 30, 2007 (2007-01-30)Chlamydia and pregnancy due to rape
House beats the drug charges and is back at the hospital after a short stint in rehab. Tired of House's disdain for patients, Cuddy turns his clinic duty into a game, with the stakes raised to a level that speaks to House: challenge. When he encounters Eve, who is tested positive for an STD and admits she has very recently been raped, she refuses to be treated by anyone but House. Meanwhile, Cameron encounters a homeless man (guest star Geoffrey Lewis) who is very different from how he originally seems.
59 (3-13)"Needle in a Haystack"Peter O'FallonDavid FosterFebruary 6, 2007 (2007-02-06)Undigested toothpick
16 year-old Stevie Lipa is admitted to Princeton-Plainsboro with a serious respiratory condition and internal bleeding. He is assigned to House, but he is busy fulfilling a dare given to him by Cuddy. A startling secret is revealed about Stevie, and the team encounters troubles with his parents, thus Foreman is forced to ask Stevie to lie directly to his parents, risking his medical license.
60 (3-14)"Insensitive"Deran SarafianMatthew V. LewisFebruary 13, 2007 (2007-02-13)Diphyllobothrium latum causing Vitamin B12 deficiency
A girl (Mika Boorem) with CIPA, a rare condition in which the sufferer cannot feel pain, gets in a car accident. Once her testing is done, she begins developing high fevers with multiple seizures and is rapidly deteriorating.
61 (3-15)"Half-Wit"Katie JacobsLawrence KaplowMarch 6, 2007 (2007-03-06)Takayasu's arteritis
A brain-damaged musical savant (guest star Dave Matthews) has seizures despite being on anti-seizure medications. When everyone learns that House has entered himself for brain cancer treatment, they attempt to comfort him, but House simply turns them away.
62 (3-16)"Top Secret"Deran SarafianThomas L. MoranMarch 27, 2007 (2007-03-27)Hereditary hemorrhagic telangiectasia
House treats a U.S. Marine returning from Iraq, who has symptoms consistent with Gulf War Syndrome. However, following a dream about the Marine, the case becomes more complicated, alongside a physical problem that House has to overcome.
63 (3-17)"Fetal Position"Matt ShakmanRussel Friend & Garrett LernerApril 3, 2007 (2007-04-03)
A famous, pregnant photographer, Emma Sloan, is brought to the hospital after suffering a stroke in the middle of a photo shoot. Although Emma's condition initially stabilizes, her health takes a turn for the worse when her kidneys fail and Emma is more concerned about her baby's well-being than her own. Meanwhile, the secret relationship between Cameron and Chase is exposed to Foreman and Cuddy, and House makes extravagant plans to take a much-needed vacation.
64 (3-18)"Airborne"Elodie KeeneDavid HoseltonApril 10, 2007 (2007-04-10)
House and Cuddy face a widespread outbreak on their plane back from a symposium in Singapore, while Wilson and the rest of the team treat a woman with constant seizures.
65 (3-19)"Act Your Age"Daniel SackheimSara HessApril 17, 2007 (2007-04-17)Precocious puberty due to externally applied testosterone
A six year-old girl suffers ailments expected in much older patients. Tensions mount between Chase and Cameron, leading House to intentionally assign them to the same tasks, including investigating the young girl's home, where they find something possibly incriminating on the girl's father.
66 (3-20)"House Training"Paul McCraneDoris EganApril 24, 2007 (2007-04-24)Staphylococcus aureus infection
A scam artist loses her ability to make decisions. While House and the team struggle to find the underlying cause, the case becomes personal for Foreman.
67 (3-21)"Family"David StraitonLiz FriedmanMay 1, 2007 (2007-05-01)Histoplasmosis
A 14 year-old leukemia patient's only hope of survival is a bone marrow transplant from his younger brother, but when he gets sick, the team must race against time to save both sibilings. Meanwhile, Foreman must deal with the consequences of the previous case.
68 (3-22)"Resignation"Martha MitchellPamela DavisMay 8, 2007 (2007-05-08)
Speculation over Foreman's resignation continues, while a young girl named Addie is admitted after bleeding from the mouth during martial arts practice and House and Wilson are secretly concerned about each other.
69 (3-23)"The Jerk"Daniel SackheimLeonard DickMay 15, 2007 (2007-05-15)Haemochromatosis
House meets his match in the form of Nate, an obnoxious 16 year-old chess prodigy with intense head pain and behavioral issues, who manages to annoy and offend every member of the team during his course of treatment. Meanwhile, Foreman's frustration with House reaches a new level when he believes House sabotages his job interview with another hospital.
70 (3-24)"Human Error"Katie JacobsThomas L. Moran & Lawrence KaplowMay 29, 2007 (2007-05-29)Congenital heart defect (infected third coronary artery ostium)
House and the team take on the case of a young woman who, along with her husband, is rescued at sea en route from Cuba in a desperate attempt to personally see House and get a diagnosis for her illness. During her stay in the hospital, she develops a new symptom: her heart stops – but she miraculously keeps talking. Foreman prepares for his last day at Princeton-Plainsboro Teaching Hospital. Chase is fired by House when he tries to confront him and Cameron resigns.