Roth's spot: Difference between revisions
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'''Roth's spots''' are [[retina]]l [[hemorrhage]]s with white or pale centers composed of [[coagulate]]d [[fibrin]]. They are typically observed via [[fundoscopy]] (using an [[ophthalmoscope]] to view inside the [[human eye|eye]]) or slit lamp exam. |
'''Roth's spots''' are [[retina]]l [[hemorrhage]]s with white or pale centers. The original retinal spots identified in 1872 were attributed to nerve-fibres that had burst or exploded. Present-day analysis shows that they can be composed of [[coagulate]]d [[fibrin]] including [[platelets]], focal ischemia, inflammatory infiltrate, infectious organisms, or neoplastic cells.<ref name=NEJM>{{cite web|last1=Lepore|first1=Frederick|title=MD|url=focal ischemia, inflammatory infiltrate, a colony of infectious organisms, fibrin and platelets, or an accumulation of neoplastic cells|website=New England Journal of Medicine|accessdate=19 June 2014}}</ref> They are typically observed via [[fundoscopy]] (using an [[ophthalmoscope]] to view inside the [[human eye|eye]]) or slit lamp exam. |
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They are usually caused by immune complex mediated vasculitis often resulting from bacterial [[endocarditis]]. |
They are usually caused by immune complex mediated vasculitis often resulting from bacterial [[endocarditis]]. |
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Revision as of 01:04, 19 June 2014
Roth's spots are retinal hemorrhages with white or pale centers. The original retinal spots identified in 1872 were attributed to nerve-fibres that had burst or exploded. Present-day analysis shows that they can be composed of coagulated fibrin including platelets, focal ischemia, inflammatory infiltrate, infectious organisms, or neoplastic cells.[1] They are typically observed via fundoscopy (using an ophthalmoscope to view inside the eye) or slit lamp exam.
They are usually caused by immune complex mediated vasculitis often resulting from bacterial endocarditis. Roth's spots may be observed in leukemia, diabetes, subacute bacterial endocarditis, pernicious anemia, ischemic events, and rarely in HIV retinopathy.
Roth's spots are named after Moritz Roth.[2][3]
See also
References
- ^ Lepore, Frederick. [focal ischemia, inflammatory infiltrate, a colony of infectious organisms, fibrin and platelets, or an accumulation of neoplastic cells "MD"]. New England Journal of Medicine. Retrieved 19 June 2014.
{{cite web}}: Check|url=value (help) - ^ synd/2684 at Who Named It?
- ^ M. Roth. Über Netzhautaffectionen bei Wundfiebern. I. Die embolische Panophthalmitis. Deutsche Zeitschrift für Chirurgie, Leipzig, 1872, 1: 471-484.
External links
Template:Eponymous medical signs for cardiovascular system
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