SARS-CoV-2: Difference between revisions
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== Virology == |
== Virology == |
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Sequences of Wuhan betacoronavirus show similarities to [[betacoronavirus]]es found in [[bat]]s, but is genetically distinct from other [[coronavirus]]es such as ''[[Severe acute respiratory syndrome-related coronavirus]]'' and ''[[Middle East respiratory syndrome-related coronavirus]]''.<ref name=":1" /> Five genomes of the novel coronavirus have been isolated and reported including BetaCoV/Wuhan/IVDC-HB-01/2019, BetaCoV/Wuhan/IVDC-HB-04/2020, BetaCoV/Wuhan/IVDC-HB-05/2019, BetaCoV/Wuhan/WIV04/2019, and BetaCoV/Wuhan/IPBCAMS-WH-01/2019 from the [[Chinese Center for Disease Control and Prevention|China CDC]] [[National Institute for Viral Disease Control and Prevention]], [[Institute of Pathogen Biology]], and [[Wuhan Jinyintan Hospital]].<ref name=":1" /><ref>{{cite web|url=http://virological.org/t/initial-genome-release-of-novel-coronavirus/319|title=Initial genome release of novel coronavirus|date=2020-01-11|website=Virological|language=en-US|access-date=2020-01-12}}</ref> Its [[RNA]] sequence is approximately 30k [[nucleotide]]s in length.<ref name=":1" /> |
Sequences of Wuhan betacoronavirus show similarities to [[betacoronavirus]]es found in [[bat]]s, but is genetically distinct from other [[coronavirus]]es such as ''[[Severe acute respiratory syndrome-related coronavirus]]'' and ''[[Middle East respiratory syndrome-related coronavirus]]''.<ref name=":1" /><ref>{{cite web |title=Phylogeny of SARS-like betacoronaviruses |url=https://nextstrain.org/groups/blab/sars-like-cov |website=nextstrain |accessdate=18 January 2020}}</ref> Five genomes of the novel coronavirus have been isolated and reported including BetaCoV/Wuhan/IVDC-HB-01/2019, BetaCoV/Wuhan/IVDC-HB-04/2020, BetaCoV/Wuhan/IVDC-HB-05/2019, BetaCoV/Wuhan/WIV04/2019, and BetaCoV/Wuhan/IPBCAMS-WH-01/2019 from the [[Chinese Center for Disease Control and Prevention|China CDC]] [[National Institute for Viral Disease Control and Prevention]], [[Institute of Pathogen Biology]], and [[Wuhan Jinyintan Hospital]].<ref name=":1" /><ref>{{cite web|url=http://virological.org/t/initial-genome-release-of-novel-coronavirus/319|title=Initial genome release of novel coronavirus|date=2020-01-11|website=Virological|language=en-US|access-date=2020-01-12}}</ref> Its [[RNA]] sequence is approximately 30k [[nucleotide]]s in length.<ref name=":1" /> |
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== References == |
== References == |
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Revision as of 15:57, 18 January 2020
 | This article needs more reliable medical references for verification or relies too heavily on primary sources. (January 2020) |  |
| Novel coronavirus (2019-nCoV) | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | incertae sedis |
| Virus: | Novel coronavirus (2019-nCoV)
|
| Synonyms | |
| |
| NCBI genome ID | MN908947 |
|---|---|
| Genome size | 30473 bp |
| Year of completion | 2020 |
Novel coronavirus (2019-nCoV) as denoted by WHO,[1][2] also known as Wuhan coronavirus or Wuhan seafood market pneumonia virus,[3] is a positive-sense, single-stranded RNA coronavirus first reported in 2019 and genomically sequenced after nucleic acid testing on a positive patient sample in a patient with pneumonia during the 2019-2020 Wuhan pneumonia outbreak.[4][5][6]
According to WHO, there may have been limited human-to-human transmission of this coronavirus within patient families, and a wider outbreak is possible. No specific treatment for the new virus is currently available, but existing anti-virals could be "re-purposed". [7]
Virology
Sequences of Wuhan betacoronavirus show similarities to betacoronaviruses found in bats, but is genetically distinct from other coronaviruses such as Severe acute respiratory syndrome-related coronavirus and Middle East respiratory syndrome-related coronavirus.[6][8] Five genomes of the novel coronavirus have been isolated and reported including BetaCoV/Wuhan/IVDC-HB-01/2019, BetaCoV/Wuhan/IVDC-HB-04/2020, BetaCoV/Wuhan/IVDC-HB-05/2019, BetaCoV/Wuhan/WIV04/2019, and BetaCoV/Wuhan/IPBCAMS-WH-01/2019 from the China CDC National Institute for Viral Disease Control and Prevention, Institute of Pathogen Biology, and Wuhan Jinyintan Hospital.[6][9] Its RNA sequence is approximately 30k nucleotides in length.[6]
References
- ^ Surveillance case definitions for human infection with novel coronavirus (nCoV)
- ^ "Novel coronavirus (2019-nCoV), Wuhan, China". Cdc.gov. 2020-01-10. Retrieved 2020-01-16.
- ^ Zhang, Y.-Z.; et al. (12 January 2020). "Wuhan seafood market pneumonia virus isolate Wuhan-Hu-1, complete genome". GenBank. Bethesda MD. Retrieved 13 January 2020.
- ^ "中国疾病预防控制中心". www.chinacdc.cn. Retrieved 2020-01-09.
- ^ "New-type coronavirus causes pneumonia in Wuhan: expert – Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 2020-01-09.
- ^ a b c d "CoV2020". platform.gisaid.org. Retrieved 2020-01-12.
{{cite web}}: CS1 maint: url-status (link) - ^ WHO says new China coronavirus could spread, warns hospitals worldwide
- ^ "Phylogeny of SARS-like betacoronaviruses". nextstrain. Retrieved 18 January 2020.
- ^ "Initial genome release of novel coronavirus". Virological. 2020-01-11. Retrieved 2020-01-12.