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The '''Genographic Project''', launched on 13 April 2005 by the [[National Geographic Society]] and [[IBM]], is a multi-year genetic anthropology study that aims to map historical human [[Historical migration|migration]] patterns by collecting and analyzing [[DNA]] samples.<ref name="ResponsibleGenographics">http://www.gene-watch.org/programs/privacy/ResponsibleGenographics.html</ref> As of 2017, over 890,000 participants in over 140 countries have joined the project.<ref>https://genographic.nationalgeographic.com</ref>
The '''Genographic Project''', launched on 13 April 2005 by the [[National Geographic Society]] and [[IBM]], is a multi-year genetic anthropology study that aims to map historical human [[Historical migration|migration]] patterns by collecting and analyzing [[DNA]] samples.<ref name="ResponsibleGenographics">{{cite web |url=http://www.gene-watch.org/programs/privacy/ResponsibleGenographics.html |title=Archived copy |accessdate=2015-05-16 |deadurl=yes |archiveurl=https://web.archive.org/web/20080516054252/http://www.gene-watch.org/programs/privacy/ResponsibleGenographics.html |archivedate=16 May 2008 |df=dmy-all }}</ref> As of 2017, over 890,000 participants in over 140 countries have joined the project.<ref>https://genographic.nationalgeographic.com</ref>


==Overview==
==Overview==

Revision as of 21:32, 12 October 2017

The Genographic Project, launched on 13 April 2005 by the National Geographic Society and IBM, is a multi-year genetic anthropology study that aims to map historical human migration patterns by collecting and analyzing DNA samples.[1] As of 2017, over 890,000 participants in over 140 countries have joined the project.[2]

Overview

Part of a series on
Genetic genealogy
Concepts
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Created and led by project director Dr. Spencer Wells from 2005 to 2015, field researchers at 11 regional centers around the world collect DNA samples from indigenous populations. Since the fall of 2015, the Project has been led by Dr. Miguel Vilar. The project also sells self-testing kits to members of the general public.

The project is a privately funded, not-for-profit collaboration between the National Geographic Society, IBM and the Waitt Foundation.

In Fall 2012, The Genographic Project announced the completion of a new genotyping array, dedicated to Genetic Anthropology, called the GenoChip. GenoChip is specifically designed for anthropological testing and includes SNPs from autosomal DNA, X-chromosome DNA, Y-chromosome DNA and mitochondrial DNA (mtDNA). The design of the new chip was a collaborative effort between Spencer Wells of National Geographic, Dr. Eran Elhaik of Johns Hopkins, Family Tree DNA, and Illumina.[3]

In the fall of 2015 a new chip was designed as a joint effort between Dr. Miguel Vilar, current Genographic Lead Scientist, and Family Tree DNA.

Geno 2.0

The Admixture test developed by Wells and Elhaik classifies individuals by assessing their proportions of genomic ancestry related to nine ancestral regions: Northeast Asian, Mediterranean, Southern African, Southwest Asian, Oceanian, Southeast Asian, Northern European, Sub-Saharan African and Native American.[4]

Population Mediterranean Northern European Southwest Asian Sub-Saharan African Southern African Northeast Asian Southeast Asian Native American Oceanian Total
African American 6 10 4 73 4 2 99
Altaian 2 17 22 53 4 98
Amerindian 4 5 3 4 83 99
Bermudian 15 20 7 48 3 7 4 100
British 33 50 17 100
Bulgarian 47 31 20 2 100
Chinese 72 28 100
Danish 30 53 16 99
Dominican 29 11 1 47 1 1 1 4 95
Eastern Indian 2 2 43 50 2 99
Egyptian 65 18 14 97
Finnish 17 57 17 7 98
Georgian 61 7 31 99
German 36 46 17 99
Greek 54 28 17 99
Iberian 48 37 13 98
Iranian 42 8 42 5 97
Japanese 75 25 100
Khoisan 47 52 99
Kinh 57 43 100
Kuwaiti 57 4 27 8 2 98
Lebanese 66 5 26 2 99
Luhya 2 89 8 99
Malagasy 2 57 4 15 20 98
Mexican 28 20 8 4 2 36 98
Mongolian 6 12 67 9 4 98
Northern Caucasian 46 16 33 4 99
Northern Indian 6 5 34 26 27 98
Oceanian 12 88 100
Papuan 5 4 91 100
Highland Peruvian 2 2 95 99
Peruvians 15 10 3 2 68 98
Puerto Rican 31 21 9 25 2 11 99
Romanian 43 36 19 2 100
Russians 25 51 18 4 98
Sardinian 67 24 8 99
Southern Indian 4 2 58 35 99
Tajikistan 22 22 44 10 98
Tatar 21 40 21 16 98
Tunisian 62 6 10 19 2 99
Tuscan 54 28 17 99
Vanuatu 4 15 78 97
Western Indian 9 6 58 26 99
Yoruban 97 3 100

Geno 2.0 Next Generation

Geno 2.0 Next Generation is the current phase of the Genographic Project. As compared to earlier phases which used nine regional affiliations, Geno 2.0 Next Generation analyzes modern-day indigenous populations around the world carry using either 18 or 22 regional affiliations.[5] A DNA-testing kit requiring a saliva sample from a user is analyzed for genomic identifiers that offer unprecedented insight into the user's genetic origins.[6]

Citizen involvement

Since 2005 Genographic has used volunteers (in fieldwork and providing DNA samples) and citizen science projects. Such outreach for public participation in research has been encouraged by organizations such as International Society of Genetic Genealogy (ISOGG), which is seeking to promote benefits from scientific research.[7][8][9] This includes supporting, organization and dissemination of personal DNA (genetic) testing.

The International Society of Genetic Genealogy (ISOGG) supports citizen participation in genetic research,[10] and believes such volunteers have provided valuable information and research to the professional scientific community.[11]

In a 2013 speech to the Southern California Genealogical Society, Spencer Wells, Director of the Genographic Project, discussed its encouragement of citizen scientists:

Since 2005, the Genographic Project has used the latest genetic technology to expand our knowledge of the human story, and its pioneering use of DNA testing to engage and involve the public in the research effort has helped to create a new breed of "citizen scientist." Geno 2.0 expands the scope for citizen science, harnessing the power of the crowd to discover new details of human population history.[12]

Human rights criticism

See also: Archaeology of the Americas and Models of migration to the New World

Shortly after the announcement of the project in April 2005, the Indigenous Peoples Council on Biocolonialism (IPCB), based in Nevada, released a statement criticizing the project: spokespersons noted its connections to controversial issues raised by the Human Genome Diversity Project, which had government overview, unlike this private project. The IPCB recommended against indigenous people participating.[13] It also recommended that indigenous peoples boycott IBM, Gateway Computers, and National Geographic, which are collaborating on the Genographic Project.

In May 2006, some indigenous representatives went to United Nations Permanent Forum on Indigenous Issues (UNPFII) to contest participation in genetic testing. A spokesman said,

"The Genographic Project is exploitative and unethical because it will use Indigenous peoples as subjects of scientific curiosity in research that provides no benefit to Indigenous peoples, yet subjects them to significant risks. Researchers will take blood or other bodily tissue samples for their own use in order to further their own speculative theories of human history".[1]

UNPFII conducted investigations into the objectives of the Genographic Project, and concluded that, since the project was "conceived and has been initiated without appropriate consultation with or regard for the risks to its subjects, the Indigenous peoples, the Council for Responsible Genetics concludes that the Indigenous peoples' representatives are correct and that the Project should be immediately suspended".[1]

Around May 2006, the UNPFII recommended that National Geographic and other sponsors suspend the project.[14][15] Concerns were that the knowledge gleaned from the research could clash with long-held beliefs of indigenous peoples and threaten their cultures. There were also concerns that indigenous claims to land rights and other resources could be threatened.

As of December 2006, some federally recognized tribes in the United States have declined to take part in the study. "What the scientists are trying to prove is that we're the same as the Pilgrims except we came over several thousand years before", said Maurice Foxx, chairman of the Massachusetts Commission on Indian Affairs and a member of the Mashpee Wampanoag. "Why should we give them that openly?"[14] Not all peoples agree with his position. as of December 2012, more than 70,000 indigenous participants from the Americas, Africa, Asia, Europe, and Oceania had joined the project.[citation needed]

See also

References

  1. ^ a b c "Archived copy". Archived from the original on 16 May 2008. Retrieved 16 May 2015. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)CS1 maint: archived copy as title (link)
  2. ^ https://genographic.nationalgeographic.com
  3. ^ http://gbe.oxfordjournals.org/content/5/5/1021.full.pdf+html
  4. ^ Who Am I: Regions Overview
  5. ^ https://genographic.nationalgeographic.com/reference-populations-next-gen/
  6. ^ https://genographic.nationalgeographic.com/about/
  7. ^ Bonney, R. and LaBranche, M. (2004). "Citizen Science: Involving the Public in Research," ASTC Dimensions, May/June 2004, p. 13.
  8. ^ Baretto, C., Fastovsky, D. and Sheehan, P. (2003). "A Model for Integrating the Public into Scientific Research," Journal of Geoscience Education, 50 (1). pp. 71–75.
  9. ^ McCaffrey, R.E. (2005). "Using Citizen Science in Urban Bird Studies," Urban Habitats, 3 (1). pp. 70–86.
  10. ^ King, Turi E.; Jobling, Mark A. (2009). "What's in a name? Y chromosomes, surnames and the genetic genealogy revolution". Trends in Genetics. 25 (8): 351–60. doi:10.1016/j.tig.2009.06.003. PMID 19665817. The International Society of Genetic Genealogy (www.isogg.org) advocates the use of genetics as a tool for genealogical research, and provides a support network for genetic genealogists. It hosts the ISOGG Y-haplogroup tree, which has the virtue of being regularly updated.
  11. ^ Mendex, etc. al., Fernando (28 February 2013). "An African American Paternal Lineage Adds an Extremely Ancient Root to the Human Y Chromosome Phylogenetic Tree". The American Society of Human Genetics. pp. 454–459. Retrieved 10 July 2013.
  12. ^ Wells, Spencer (2013). "The Genographic Project and the Rise of Citizen Science". Southern California Genealogical Society (SCGS). Archived from the original on 10 July 2013. Retrieved July 10, 2013. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  13. ^ Harry, Debra and Le'a Malia Kanehe. "Genetic Research: Collecting Blood to Preserve Culture?" Cultural Survival, 29.4 (Winter 2005). Accessed 4 February 2014.
  14. ^ a b Harmon, Amy (10 December 2006). "DNA Gatherers Hit Snag: Tribes Don't Trust Them". The New York Times.
  15. ^ "United Nations Recommends Halt to Genographic Project". ipcb.

Official sites

Supporting participants

News articles

Videos

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