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In [[pathology]], the '''Grocott-Gomori's''' (or '''Gömöri''') '''[[methenamine silver stain]]''', abbreviated '''GMS''', is a popular [[staining]] method in [[histology]]. The stain was originally named after [[György Gömöri|György Gömori]], the Hungarian physician who developed the stain.
In [[pathology]], the '''Grocott-Gomori's''' (or '''Gömöri''') '''[[methenamine silver stain]]''', abbreviated '''GMS''', is a popular [[staining]] method in [[histology]]. The stain was originally named after [[György Gömöri|György Gömori]], the Hungarian physician who developed the stain.


It is used widely as a screen for [[fungi|fungal]] [[microorganisms|organism]]s.<ref>{{cite journal |last1=Khalid |first1=Mohamed |title=LABORATORY DIAGNOSIS OF THE CAUSATIVE DERMATOPHYTES OF TINEA CAPITIS |journal=World Journal of Pharmaceutical Research |date=2019 |volume=8 |issue=6 |page=85-99 |doi=10.20959/wjpr20196-14850 |url=http://www.wjpr.net/download/article/1556607368.pdf |accessdate=4 May 2019}}</ref> Particularly useful in staining carbohydrates.
It is used widely as a screen for [[fungi|fungal]] [[microorganisms|organism]]s. Particularly useful in staining carbohydrates.


It can be used to identify the yeast-like fungus ''[[Pneumocystis jiroveci]]''<ref name="pmid17041954">{{cite journal |vauthors=Nassar A, Zapata M, Little JV, Siddiqui MT |title=Utility of reflex gomori methenamine silver staining for ''Pneumocystis jirovecii'' on bronchoalveolar lavage cytologic specimens: A review |journal=Diagn. Cytopathol. |volume=34 |issue=11 |pages=719–23 |date=November 2006 |pmid=17041954 |doi=10.1002/dc.20540 }}</ref> which causes a form of [[pneumonia]] called [[Pneumocystis pneumonia|''Pneumocystis'' pneumonia]] (PCP) or [[pneumocystosis]].
It can be used to identify the yeast-like fungus ''[[Pneumocystis jiroveci]]''<ref name="pmid17041954">{{cite journal |vauthors=Nassar A, Zapata M, Little JV, Siddiqui MT |title=Utility of reflex gomori methenamine silver staining for ''Pneumocystis jirovecii'' on bronchoalveolar lavage cytologic specimens: A review |journal=Diagn. Cytopathol. |volume=34 |issue=11 |pages=719–23 |date=November 2006 |pmid=17041954 |doi=10.1002/dc.20540 }}</ref> which causes a form of [[pneumonia]] called [[Pneumocystis pneumonia|''Pneumocystis'' pneumonia]] (PCP) or [[pneumocystosis]].

Revision as of 18:53, 4 May 2019

A liver biopsy stained using the grocott's methenamine silver stain demonstrating histoplasma (black round balls) in a granuloma.

In pathology, the Grocott-Gomori's (or Gömöri) methenamine silver stain, abbreviated GMS, is a popular staining method in histology. The stain was originally named after György Gömori, the Hungarian physician who developed the stain.

It is used widely as a screen for fungal organisms. Particularly useful in staining carbohydrates.

It can be used to identify the yeast-like fungus Pneumocystis jiroveci[1] which causes a form of pneumonia called Pneumocystis pneumonia (PCP) or pneumocystosis.

The cell walls of these organisms are outlined by the brown to black stain.

See also

References

  1. ^ Nassar A, Zapata M, Little JV, Siddiqui MT (November 2006). "Utility of reflex gomori methenamine silver staining for Pneumocystis jirovecii on bronchoalveolar lavage cytologic specimens: A review". Diagn. Cytopathol. 34 (11): 719–23. doi:10.1002/dc.20540. PMID 17041954.