6-aminohexanoate-dimer hydrolase

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6-aminohexanoate-dimer hydrolase
Identifiers
EC number 3.5.1.46
CAS number 75216-15-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 6-aminohexanoate-dimer hydrolase (EC 3.5.1.46) is an enzyme that catalyzes the chemical reaction

N-(6-aminohexanoyl)-6-aminohexanoate + H2O 2 6-aminohexanoate

Thus, the two substrates of this enzyme are N-(6-aminohexanoyl)-6-aminohexanoate and H2O, whereas its product is 6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase. This enzyme is also called 6-aminohexanoic acid oligomer hydrolase.

Structural studies[edit]

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1WYB, 1WYC, and 2DCF.

See also[edit]

References[edit]

  • Okada H; Terada, T; Taniguchi, T; Takene, Y; Masuda, S; Matsunaga, N; Okada, H (1981). "Purification and characterization of 6-aminohexanoic-acid-oligomer hydrolase of Flavobacterium sp. Ki72". Eur. J. Biochem. 116 (3): 547–51. PMID 7262074. doi:10.1111/j.1432-1033.1981.tb05371.x.