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Chlorproguanil

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Chlorproguanil
Names
IUPAC name
1-[Amino-(3,4-dichloroanilino)methylidene]-2-propan-2-ylguanidine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.007.875 Edit this at Wikidata
UNII
  • InChI=1S/C11H15Cl2N5/c1-6(2)16-10(14)18-11(15)17-7-3-4-8(12)9(13)5-7/h3-6H,1-2H3,(H5,14,15,16,17,18) ☒N
    Key: ISZNZKHCRKXXAU-UHFFFAOYSA-N ☒N
  • InChI=1/C11H15Cl2N5/c1-6(2)16-10(14)18-11(15)17-7-3-4-8(12)9(13)5-7/h3-6H,1-2H3,(H5,14,15,16,17,18)
    Key: ISZNZKHCRKXXAU-UHFFFAOYAU
  • Clc1ccc(NC(=N/C(=N/C(C)C)N)N)cc1Cl
Properties
C11H15Cl2N5
Molar mass 288.18 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chlorproguanil is an antimalarial drug.[1]

References

  1. ^ Fanello, Caterina I.; Karema, Corine; Avellino, Pamela; Bancone, Germana; Uwimana, Aline; Lee, Sue J.; d'Alessandro, Umberto; Modiano, David (2008). "High Risk of Severe Anaemia after Chlorproguanil-Dapsone+Artesunate Antimalarial Treatment in Patients with G6PD (A-) Deficiency". PLOS ONE. 3 (12): e4031. Bibcode:2008PLoSO...3.4031F. doi:10.1371/journal.pone.0004031. PMC 2603295. PMID 19112496.

See also



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