Ian Calman Muir MacLennan
Ian Calman Muir MacLennan | |
|---|---|
| Born | 30 December 1939 |
| Known for | contributions to immunology discovered marginal zone B-cells |
| Awards | FRS (2012) |
| Scientific career | |
| Fields | Immunology |
| Institutions | University of Birmingham |
Ian Calman Muir MacLennan is Emeritus Professor of Immunology at the University of Birmingham MRC Centre for Immune Regulation in Birmingham, UK.
He was born on 30 December 1939.[1] He has made pioneering contributions to immunology and was the first to discover marginal zone B-cells.
He was made a Commander of the Order of the British Empire in the Queen's Birthday Honours in 2005.[2] He was elected a Fellow of the Royal Society (FRS) in 2012, his nomination reads:
Ian MacLennan has made several landmark contributions to immunology and especially our understanding of antibody production. His classic experiments led him propose a role for germinal centres in affinity maturation of antibody responses by a process of hypermutation followed by antigen-mediated selection. Subsequently, he identified the basis of the multi-step selection process that protects against autoantibody production. He also first discovered marginal zone B cells and identified how they counter encapsulated bacterial infection. His early work revealed and characterized the cells now termed NK cells and their capacity to kill antibody-coated nucleated cells.
References
- ^ Bott, Simon, ed. (1980). Who's Who of British Scientists 1980/81 (3rd ed.). Simon Books Limited. p. 317. ISBN 9780862290016.
- ^ "Queen's Birthday Honours List", The Times Higher Education, 17 June 2005, retrieved 4 May 2015
- ^ "Professor Ian Calman Muir MacLennan CBE FMedSci FRS". The Royal Society. Retrieved 4 May 2015.
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