This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia.
Hori Y, Kobayashi T, Kikko Y, et al. (2008). "Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation.". Biochem. Biophys. Res. Commun. 373 (1): 119–24. PMID18554500. doi:10.1016/j.bbrc.2008.06.001.
Fan Y, Esmail MA, Ansley SJ, et al. (2004). "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.". Nat. Genet. 36 (9): 989–93. PMID15314642. doi:10.1038/ng1414.