Aldehyde oxidase 1

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AOX1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases AOX1, AO, AOH1, aldehyde oxidase 1
External IDs MGI: 88035 HomoloGene: 68165 GeneCards: AOX1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001159

NM_009676

RefSeq (protein)

NP_001150

NP_033806.2
NP_033806

Location (UCSC) Chr 2: 200.59 – 200.68 Mb Chr 1: 58.03 – 58.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Aldehyde oxidase 1 is an enzyme that in humans is encoded by the AOX1 gene.[3][4]

Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide.[3]

Clinical significance[edit]

Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b "Entrez Gene: aldehyde oxidase 1". 
  4. ^ a b Berger R, Mezey E, Clancy KP, Harta G, Wright RM, Repine JE, Brown RH, Brownstein M, Patterson D (March 1995). "Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis". Somat. Cell Mol. Genet. 21 (2): 121–31. doi:10.1007/BF02255787. PMID 7570184. 

External links[edit]

Further reading[edit]