Argyreia nervosa is a perennial climbing vine native to the Indian subcontinent and introduced to numerous areas worldwide, including Hawaii, Africa, and the Caribbean. Though it can be invasive, it is often prized for its aesthetic and medicinal value. Common names include Hawaiian baby woodrose, adhoguda अधोगुडा or vidhara विधारा (Sanskrit), elephant creeper and woolly morning glory. Its seeds are known for their powerful entheogenic value, greater or similar to its varieties from Convolvulaceae family, with the users reporting significant psychedelic and spiritual experiences . The two botanical varieties are A. n. var. nervosa described here, and A. n. var. speciosa, which are used in Ayurvedic medicine and have great medicinal values.
Huna shamans used them according to various oral histories. The seeds of Argyreia nervosa produce psychoactive effects. They contain ergot alkaloids varying considerably in concentration with LSA weight ranging between exactly similar looking seeds from 3 μg to 34 μg (avg 17 μg). However, LSA is about one tenth potent in its effects than its cousin LSD, making a threshold dose level for LSA about 500 μg. The psychoactive effects of the seeds may therefore be due to other alkaloids present in them and the safe and effective dose may be difficult to predict.
^ ab"Medicinal uses and biological activities of Argyreia speciosa Sweet (Hawaiian Baby Woodrose) An Overview". Indian Journal of Natural Products and Resources: 286-291. September 2011.
^E. Al-Assmar, Sami (1999). "The Seeds of the Hawaiian Baby Woodrose Are a Powerful Hallucinogen". Arch Intern Med. 159 (17): 2090.
^ abPaulke, Alexander; et al. (2015). "Studies on the alkaloid composition of the Hawaiian Baby Woodrose Argyreia nervosa, a common legal high". Forensic Science International. 249: 281–293.CS1 maint: Explicit use of et al. (link)
^Paulke, Alexander; et al. (2014). "Identification of legal highs – Ergot alkaloid patterns in two Argyreia nervosa products". Forensic Science International. 242: 62–71.CS1 maint: Explicit use of et al. (link)
^The Road to Eleusis. William Daly Rare Books. 1998. ISBN091514820X.|first1= missing |last1= in Authors list (help)