Later Hittite documents reveal that Arnuwanda had also caught this plague. His younger brother Mursili helped him with Hatti's ongoing struggles against the Kaska and Arzawa lands. In one such event, the brothers wrote to Karkiya that they would provide asylum to Manapa-Tarhunta of Seha River, who had been ousted in a coup. As a result, Manapa-Tarhunta was able to return to Seha River as its leader. (Unfortunately Manapa-Tarhunta proved faithless anyway a few years later.)
Arnuwanda eventually died of the plague and was succeeded by his brother Mursili. While Arnuwanda had long been groomed by Suppiluliuma I to be the latter's successor and was respected by Hatti's enemies, Mursili is stated in the Hittite records to be relatively young and inexperienced upon his unexpected accession to the throne.
^King (lugal) of Tarhuntassa (Bryce 1997, p. 296); apparently later Great King of Hatti (Bryce 1997, p. 354).
^Nerikkaili married a daughter of Bentesina, king of Amurru (Bryce 1997, p. 294).
^Two daughters of Hattusili III were married to the pharaoh Ramesses II; one was given the Egyptian name Ma(hor)nefrure. Another, Gassuwaliya, married into the royal house of Amurru. Kilushepa was married to a king of Isuwa. A daughter married into the royal family of Babylon. A sister of Tudhaliya IV married Sausgamuwa, king of Amurru after his father Bentesina. From Bryce (1997), pp. 294 and 312.
Janet Morris wrote a detailed biographical novel, I, the Sun, whose subject was Suppiluliuma I. Arnuwanda II is an important figure in this novel, in which all characters are from the historical record, which Dr. Jerry Pournelle called "a masterpiece of historical fiction" and about which O.M. Gurney, Hittite scholar and author of The Hittites, commented that "the author is familiar with every aspect of Hittite culture". Morris' book was republished by The Perseid Press in April 2013.
He is also a character in Chie Shinohara's historical manga Red River or Anatolia Story. In this manga he is a frail-bodied man who appoints Yuri's boyfriend, his half-brother Mursili, as his successor. He is later murdered in very shady circumstances, and Yuri is falsely accused of killing him but her maid Ursula claims that she's the true murderer and is executed. The culprit isn't found until much later.
Arnuwanda II also appears in the Historical novel, "Amarna Book I: Book of Ida" by Grea Alexander. In it, he is pitted against his brother, Mursili II, who is protecting Queen Ankhesenamun's emissary, Idaten, following the murder of their brother Prince Zannanza. This book was published by SeaMonkey Ink, LLC in 2012 and is the first of a three part trilogy.