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Skeletal formula with numbering convention
Full structural formula with aromatic bond
Ball-and-stick molecular model
Space-filling molecular model
IUPAC name
Other names
273-53-0 YesY
ChEBI CHEBI:38814 YesY
ChEMBL ChEMBL451894 YesY
ChemSpider 8873 YesY
Jmol-3D images Image
PubChem 9228
Molar mass 119.12 g·mol−1
Appearance white to light yellow solid
Melting point 27 to 30 °C (81 to 86 °F; 300 to 303 K)
Boiling point 182 °C (360 °F; 455 K)
Flash point 58 °C (136 °F; 331 K)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N verify (what isYesY/N?)
Infobox references

Benzoxazole is an aromatic organic compound with a molecular formula C7H5NO, a benzene-fused oxazole ring structure, and an odor similar to pyridine.[1][2] Alhtough benzoxazole itself is of little practical value, many derivatives of benzoxazoles are commercially important.

Being a heterocyclic compound, benzoxazole finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.


It is found within the chemical structures of pharmaceutical drugs such as flunoxaprofen. Benzoxazole derivatives are also of interest for optical brighteners in laundry detergents.[3]

4 4'-bis(benzoxazolyl)-cis-stilbene is an intensely fluorescent and its derivatives are used as optical brighteners.
2 5-bis(benzoxazol-2-yl)thiophene is also an intensely fluorescent and its derivatives are used as optical brighteners, e.g. in laundry detergents.[4]

See also[edit]


  1. ^ Katritzky, A. R.; Pozharskii, A. F. (2000). Handbook of Heterocyclic Chemistry (2nd ed.). Academic Press. ISBN 0080429882. 
  2. ^ Clayden, J.; Greeves, N.; Warren, S.; Wothers, P. (2001). Organic Chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6. 
  3. ^ E. Smulders, E. Sung "Laundry Detergents, 2. Ingredients and Products" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2012. doi:10.1002/14356007.o15_013
  4. ^ M. Amine Fourati, Thierry Maris, W. G. Skene, C. Géraldine Bazuin, and Robert E. Prud’homme "Photophysical, Electrochemical and Crystallographic Investigations of the Fluorophore 2,5-Bis(5-tert-butyl-benzoxazol-2-yl)thiophene" J. Phys. Chem. B, 2011, volume 115, 12362–12369.doi:10.1021/jp207136k