|Classification and external resources|
Comedocarcinoma is one kind of breast cancer which is most commonly very early-stage  which demonstrates central necrosis. It is a usually a type of ductal carcinoma in situ. Comedo carcinomas are usually non-infiltrating and intraductal tumors. However, there have been accounts of comedocarcinoma which has then diversified into other cell types and developed into infiltrating (invasive) ductal carcinoma. Recurrence and survival rates differ for invasive breast cancer which has originated as comedocarcinoma compared with other types of cancer cells.
The duct will have characteristic necrotic tissue with calcification that feels cord-like. Squeezing the duct will yield inspissated material that is cheese-like and similar in consistency to toothpaste.
Comedocarcinoma has also been described as a histopathological type of Sebaceous carcinoma
- Yale: Cardiothoracic Imaging - Comedocarcinoma of the right breast
- Definition: comedocarcinoma from Online Medical Dictionary
- Wellfire Interactive. "Pathology Thread". virginia.edu.
- Shahid Pervez; Hassan Khan. "Infiltrating ductal carcinoma breast with central necrosis closely mimicking ductal carcinoma in situ (comedo type): a case series". J Med Case Reports. 2007; 1: 83.
- Bonnier P1, Body G, Bessenay F, Charpin C, Fétissof F, Beedassy B, Lejeune C, Piana L. "Prognostic factors in ductal carcinoma in situ of the breast: results of a retrospective study of 575 cases.". Eur J Obstet Gynecol Reprod Biol. 1999 May;84(1):27-35.
- Comedo carcinoma entry in the public domain NCI Dictionary of Cancer Terms
- Images[dead link]
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