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Dolichol O-acyltransferase

From Wikipedia, the free encyclopedia
dolichol O-acyltransferase
Identifiers
EC no.2.3.1.123
CAS no.111839-04-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a dolichol O-acyltransferase (EC 2.3.1.123) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + dolichol CoA + dolichyl palmitate

Thus, the two substrates of this enzyme are palmitoyl-CoA and dolichol, whereas its two products are CoA and dolichyl palmitate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:dolichol O-palmitoyltransferase. This enzyme is also called acyl-CoA:dolichol acyltransferase.

References

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  • Tollbom O, Valtersson C, Chojnacki T, Dallner G (1988). "Esterification of dolichol in rat liver". J. Biol. Chem. 263 (3): 1347–52. PMID 3121628.