HLA-DO
Appearance
major histocompatibility complex, class II, DO alpha | |||||||
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Identifiers | |||||||
Symbol | HLA-DOA | ||||||
Alt. symbols | HLA-DZA, HLA-DNA | ||||||
NCBI gene | 3111 | ||||||
HGNC | 4936 | ||||||
OMIM | 142930 | ||||||
RefSeq | NM_002119 | ||||||
UniProt | Q9TQD3 | ||||||
Other data | |||||||
Locus | Chr. 6 p21.3 | ||||||
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major histocompatibility complex, class II, DO beta | |||||||
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Identifiers | |||||||
Symbol | HLA-DOB | ||||||
NCBI gene | 3112 | ||||||
HGNC | 4937 | ||||||
OMIM | 600629 | ||||||
RefSeq | NM_002120 | ||||||
UniProt | P13765 | ||||||
Other data | |||||||
Locus | Chr. 6 p21.3 | ||||||
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HLA-DO is a dimeric MHC class II protein composed of α- and β-subunits which assists in the down-regulation of HLA-DM.[1]
References
- ^ Fallas JL, Tobin HM, Lou O, Guo D, Sant'Angelo DB, Denzin LK (August 2004). "Ectopic expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation". J. Immunol. 173 (3): 1549–60. doi:10.4049/jimmunol.173.3.1549. PMID 15265882.
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: CS1 maint: multiple names: authors list (link)
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