Lysine N-acetyltransferase

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lysine N-acetyltransferase
5ec4.jpg
Lysine N-acetyltransferase (EIS) hexamer, Mycobacterium tuberculosis
Identifiers
EC number2.3.1.32
CAS number37257-12-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a lysine N-acetyltransferase (EC 2.3.1.32) is an enzyme that catalyzes the chemical reaction

acetyl phosphate + L-lysine phosphate + N6-acetyl-L-lysine

Thus, the two substrates of this enzyme are acetyl phosphate and L-lysine, whereas its two products are phosphate and N6-acetyl-L-lysine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-phosphate:L-lysine N6-acetyltransferase. Other names in common use include lysine acetyltransferase, and acetyl-phosphate:L-lysine 6-N-acetyltransferase. This enzyme participates in lysine degradation.

References[edit]

  • PAIK WK, KIM S (1964). "ENZYMIC SYNTHESIS OF EPSILON-N-ACETYL-L-LYSINE". Arch. Biochem. Biophys. 108 (2): 221&ndash, 9. doi:10.1016/0003-9861(64)90379-0. PMID 14240571.