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Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
CAS Number 42370-41-2 YesY
ATC code R05CB07
PubChem CID: 36089
Synonyms trans-p-Menth-6-ene-2,8-diol; trans-sobrerol
Chemical data
Formula C10H18O2
Molecular mass 170.249 g/mol
Physical data
Melting point 130–132 °C (266–270 °F)
Boiling point 270–271 °C (518–520 °F)
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Sobrerol is a mucolytic.


Sobrerol was discovered by Ascanio Sobrero as an oxidation product of terpenes. Later the oxidation and reduction reactions of chiral pinene lead also to several possible isomers of carvone (the corresponding cyclohexyl ketone dehydrated at the isopropyl) and sobrerol, making it possible to determine reaction mechanism and the structural properties of pinene and of other terpenes.


  • G. G. Henderson, W. J. S. Eastburn (1909). "The conversion of pinene into sobrerol". J. Chem. Soc., Trans. 95: 1465–1466. doi:10.1039/CT9099501465. 
  • H. E. Armstrong, W. J. Pope (1891). "Studies of the terpenes and allied compounds. Sobrerol, a product of the oxidation of terebenthene (oil of turpentine) in sunlight". J. Chem. Soc., Trans. 59: 315–320. doi:10.1039/CT8915900315. 
  • H. Schmidt (1953). "Über cis- und trans-Sobrerol (optisch-aktives Pinolhydrat)". Chemische Berichte 86 (11): 1437–1444. doi:10.1002/cber.19530861112. 
  • Allegra L, Bossi R, Braga PC (1981). "Action of sobrerol on mucociliary transport". Respiration 42 (2): 105–9. doi:10.1159/000194412. PMID 7313328.