Sodium periodate

Sodium periodate

Names
IUPAC name sodium periodate
Other names sodium metaperiodate
Identifiers
CAS Number	7790-28-5 Y
3D model (JSmol)	Interactive image
ChemSpider	58683
ECHA InfoCard	100.029.270
EC Number	232-197-6
PubChem CID	65184
RTECS number	SD4550000
CompTox Dashboard (EPA)	DTXSID30894075
InChI InChI=1S/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1 InChI=1/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1 Key: JQWHASGSAFIOCM-REWHXWOFAO
SMILES [O-]I(=O)(=O)=O.[Na+]
Properties
Chemical formula	NaIO4
Molar mass	213.8918 g/mol
Density	3.865 g/cm3
Melting point	300 °C
Solubility in water	soluble
Related compounds
Other anions	sodium perchlorate, sodium perbromate
Other cations	potassium periodate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Sodium periodate is the sodium salt of periodic acid. It can refer to two different chemical compounds, sodium metaperiodate (often abbreviated as m-periodate), which has the formula NaIO₄, and sodium orthoperiodate (often abbreviated as o-periodate), which has the formula Na₅IO₆. Both salts are useful in certain synthetic chemistries for the oxidative power of the periodate ion.

Properties

Density is 3.865 g cm⁻³. It is soluble in water. When heated, it decomposes to form sodium iodate (NaIO₃) and oxygen. This decomposition reaction is catalyzed by the presence of manganese(IV) oxide.

Uses

Sodium periodate is used to oxidize cellulose and create a biocompatible and biodegradable compound that can be used as suture, as a scaffold for tissue engineering, or for drug delivery.

Sodium periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups. This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin. Because the process requires vicinal diols, periodate oxidation is often used to selectively label RNA (ribose has vicinal diols) instead of DNA as deoxyribose does not have vicinal diols.