Talk:Naloxegol

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Pharmacology Mid‑importance

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Chemicals Mid‑importance

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Mid	This article has been rated as Mid-importance on the project's importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Naloxegol.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Incorrect interpretation of referenced study

In the article, reference [5] is claimed to show that

"Compared to other opioid analgesics, naloxegol causes less constipation-related side effects, while maintaining comparable levels of analgesia."

This is an incorrect conclusion. Naloxegol is not an analgesic. It relieves constipation by blocking opioid binding in the gut without affecting opioid binding in the central nervous system (where opioids produce their analgesic effect). The referenced study did not compare Naloxegol to analgesics, but rather showed that the drug reduced constipation without reducing the 2602:306:3B5A:4AD0:6D1F:CA42:FBF:799 (talk) 02:58, 24 October 2015 (UTC)effectiveness of opioid analgesics used by patients in the study.[reply]

External links modified (February 2018)

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