Professor Igor Bowmane: Professor Bowmane is an old friend and colleague of Lara Croft, working in the ancient artefact department at the university of Moscow. He contacts Lara to tell her of an ancient manuscript which recounts the legend of the Nightmare Stone. His friend Illiat is looking for the artefact, but has warned Bowmane that there are other "interested parties" looking for the manuscript.
Illiat: Illiat is an archaeologist from Peru and friend of Professor Igor Bowmane. He was last seen in the Amazon searching for the Nightmare Stone, but learned that other parties were interested in the artefact. Unsure of their motives, Illiat told them nothing. Lara was to meet him at the site of the temple, only to find his camp deserted. When Lara finds him in the temple, he is near death.
Quaxe: An evil ruler wielding great power, Quazet ruled over Maya, Inca and Aztec lands. One day the three nations battled Quaxet as three high priests imprisoned his spirit in the artefact known as the Nightmare Stone. To prevent anyone from unleashing Quaxet, the stone was locked inside an obelisk which was buried in a temple deep within the Amazon. Although Quaxet does not appear during the game, he plays an important role in the backstory of this game.