Jump to content

Tripeptidyl peptidase II

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Dcirovic (talk | contribs) at 19:57, 4 April 2016 (added Category:EC 3.4.14 using HotCat). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Template:PBB Tripeptidyl-peptidase 2 is an enzyme that in humans is encoded by the TPP2 gene.[1][2] Among other things it is heavily implicated in MHC (HLA) class-I processing, as it has both endopeptidase and exopeptidase activity.[3] Template:PBB Summary

References

  1. ^ Tomkinson B, Jonsson AK (Feb 1991). "Characterization of cDNA for human tripeptidyl peptidase II: the N-terminal part of the enzyme is similar to subtilisin". Biochemistry. 30 (1): 168–74. doi:10.1021/bi00215a025. PMID 1670990.
  2. ^ "Entrez Gene: TPP2 tripeptidyl peptidase II".
  3. ^ Reits E; Neijssen J; Herberts C; et al. (April 2004). "A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation". Immunity. 20 (4): 495–506. doi:10.1016/S1074-7613(04)00074-3. PMID 15084277. {{cite journal}}: Unknown parameter |name-list-format= ignored (|name-list-style= suggested) (help)
  • The MEROPS online database for peptidases and their inhibitors: S08.090

Further reading

Template:PBB Further reading

Template:PBB Controls

Stub icon

This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Tripeptidyl_peptidase_II&oldid=713567658"