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Hi there! I have a COI: Amgen is a client of my employer, Porter Novelli. Requesting some edits to this article to provide a more complete reflection of the company's history as depicted in independent, reliable sources over the years.

Lead

[edit]
  • Update the second mention of "Thousand Oaks, California" to just "Thousand Oaks" – not necessary to repeat the state two sentences in a row.
  • Update
Amgen's Thousand Oaks staff in 2017 numbered 5,125 (7.5% of total city employment) and included hundreds of scientists, making Amgen the largest employer in Ventura County.[1][2][3]
to
Amgen's Thousand Oaks staff in 2022 numbered approximately 5,000[4] (8.5% of total city employment)[5] and included hundreds of scientists, making Amgen the largest employer in Ventura County.[2][6] As of 2022, Amgen has approximately 24,000 staff[7] and, as of 2016, has a presence in approximately 100 countries. The company develops products in six therapeutic areas: cardiovascular disease, oncology, bone health, neuroscience, nephrology and inflammation.[8]
  • Delete
Focused on molecular biology and biochemistry, its goal is to provide a healthcare business based on recombinant DNA technology.[9]
Given that the source is more than 20 years old, I think it's fair to say this isn't the best representation of the organization's current goals.
  • Update
In 2018, the company's largest selling product lines were Neulasta, an immunostimulator used to prevent infections in patients undergoing cancer chemotherapy and Enbrel, a tumor necrosis factor blocker used in the treatment of rheumatoid arthritis and other autoimmune diseases.
to
In 2019, the company's largest selling products were Enbrel (etanercept),[10] a tumor necrosis factor blocker used in the treatment of rheumatoid arthritis and other autoimmune diseases, and Neulasta (pegfilgrastim), an immunostimulator used to prevent infections in patients undergoing cancer chemotherapy.[11]
  • Update
Other products include Epogen, Aranesp, Sensipar/Mimpara, Nplate, Vectibix, Prolia and XGEVA.
to include recent products, as follows:
Other marketed products include Evenity (romosozumab-aqqg), Otezla (apremilast), Prolia (denosumab), Repatha (evolocumab), and Lumakras (sotorasib).
  • Move
Amgen sponsored the Tour of California from 2011 to 2017.[12]
from the lead into the History section.

History

[edit]
  • Move the following sentence from the intro into the history section as the first sentence:
Amgen was established in Thousand Oaks, California, in 1980.

Timeline

[edit]
  • Add to beginning of "1980" bullet:
Founded in Thousand Oaks, California, as Applied Molecular Genetics, Amgen was backed by a small group of venture capitalists. Its focus in early days was on recombinant DNA technology and recombinant human insulin.[13]
  • Add to end of "1980" bullet:
In October, Amgen named George Rathmann its first president and chief executive officer.[13]
  • Add:
  • 1983. On June 17, Amgen went public, selling two million common shares and raising nearly $40 million.[14][15][16] That same year, after more than two years of work, an Amgen research team led by Fu-Kuen Lin had a breakthrough in finding and cloning the erythropoietin gene, a protein created in the kidney that stimulates red blood cell production. Lin's team created what would become Epogen (epoetin alfa).[17][18]
  • 1984. In June, Amgen and Kirin formed a joint venture giving Kirin the rights to Epogen in Japan.[19]
  • 1985. Amgen researcher Larry Souza and his team cloned granulocyte colony-stimulating factor (G-CSF), leading to the development of Neupogen (filgrastim).[18][20][21]
  • 1988. In October, Gordon Binder was named CEO, succeeding George Rathmann.[22]
  • Update
  • 1989. Amgen received approval for the first recombinant human erythropoetin product, Epogen, for the treatment of anemia associated with chronic kidney failure. Epogen (also marketed by Johnson and Johnson under the tradename Procrit) would later be approved for anemia due to cancer chemotherapy, anemia due to treatment with certain HIV drugs, and for the reduction of the need for transfusions associated with surgery.[23]
to
  • 1989. Amgen received approval for the first recombinant human erythropoetin product, Epogen (epoetin alfa).[23][24]
The synopsis currently in the article doesn't reflect the product label.
  • Add:
  • 1993. In March, Amgen opened a new manufacturing facility in Puerto Rico, which later became the company's flagship manufacturing site.[25]
  • 1994. Amgen became the fifth company to receive the U.S. Department of Commerce's National Medal of Technology and Innovation, in recognition of its work developing medicines to improve quality of life for kidney and cancer patients.[26] Also around this time, Amgen researcher Steve Elliott and his team added more sugar molecules to erythropoietin, causing it to remain in the body longer. This led to the development of Aranesp (darbepoetin alfa).[27]
  • Add:
  • 2000. In May, Kevin Sharer became Amgen's third CEO, following Gordon Binder's retirement.[28]
  • 2001. Aranesp received FDA approval in September.[29]
  • 2002. At the beginning of the year, the FDA approved Neulasta.[30] In July, Amgen acquired Immunex, the developer of Enbrel (etanercept).[31]
  • 2004. Sensipar (cinacalcet) was approved by the FDA.[32][33] Also, Amgen acquired Tularik, another biotechnology company, expanding the company's research and development pipeline.[34][35]
  • 2006. In April, Amgen acquired Abgenix, the developer of Vectibix (panitumumab), a treatment developed for certain patients with metastatic colorectal cancer.[36] Vectibix was approved by the FDA in September 2006.[37]
  • 2008. In August, Nplate (romiplostim) was approved by the FDA.[38][39]
  • Add:
  • Add:
  • 2012. Amgen acquired Micromet, a company focused on BiTE technology, in March.[44] In May, Kevin Sharer retired, and Robert Bradway, formerly Amgen's president and chief operating officer, became CEO.[45] In June, Amgen acquired Turkish company Mustafa Nevzat Pharmaceuticals, expanding Amgen's presence in Turkey and nearby areas.[46] In July, Amgen acquired KAI Pharmaceuticals, developer of Parsabiv (etelcalcetide).[47][48] Amgen acquired Iceland-based deCODE Genetics in December.[49] Amgen also opened an affiliate in China.[50][51]
  • 2013. In October, Amgen acquired Onyx Pharmaceuticals, developer of Kyprolis (carfilzomib).[52]
  • Add:
  • 2014. In November, construction was completed on Amgen's next-generation biomanufacturing facility in Singapore.[53] Blincyto (blinatumomab) was approved by the FDA in December.[54][55]
  • Add to beginning of "2015" bullet:
Repatha (evolocumab) was approved by the FDA in August.[56]
  • Add to end of "2015" bullet:
In October, the FDA approved Imlygic.[57]
  • Add to end of "2016" bullet:
Also in September, the FDA approved Amjevita (adalimumab-atto).[58]
  • Add to end of "2017" bullet:
The FDA approved Parsabiv in February[59] and Mvasi (bevacizumab-awwb) in September.[60] In October, the Amgen Foundation pledged $3 million to Khan Academy to support the development of free online biology lessons.[61][62]
  • Add to end of "2018" bullet:
In May, Aimovig (erenumab-aooe) was approved by the FDA.[63] Amgen began constructing a next-generation biomanufacturing plant at its West Greenwich, Rhode Island, campus in July.[64]
  • Add to beginning of "2019" bullet:
In January, Evenity (romosozumab) received approval in Japan,[65][66] followed by FDA approval in April.[67] In June, Kanjinti (trastuzumab-anns) was approved by the FDA.[68]
  • Add to end of "2019" bullet:
In December, the FDA approved Avsola (infliximab-axxq).[69]
  • Add:
  • 2020. In January, the Amgen Foundation and Harvard University debuted LabXchange, a free online science education platform.[70][71] Amgen and the Amgen Foundation announced a commitment of up to $12.5 million to support COVID-19 relief efforts in March.[72] In April, Amgen established Amgen K.K. as the company’s wholly-owned affiliate in Japan.[73][74] Amgen announced in July that the United States Court of Appeals for the Federal Circuit had upheld the validity of two Amgen patents that described and claimed Enbrel and methods for making it. The appellate court affirmed an August 2019 decision by the United States District Court for the District of New Jersey and rejected Sandoz's attempt to invalidate the patents on Enbrel.[75] Also in July, Amgen granted an additional $3 million Khan Academy to support educational equity and science learning.[76][77] Amgen joined the Dow Jones Industrial Average on August 24, 2020.[78] In September, Amgen and Eli Lilly and Company announced a global manufacturing collaboration for COVID-19 antibody therapies.[79] On December 10, Amgen announced that it joined OneTen, a coalition of large employers that aims to hire and advance one million black Americans over the next ten years.[80] Later that month, the FDA approved Riabni (rituximab-arrx), a biosimilar to Rituxan.[81]
  • Add to "2021" bullet, before "In July,":
The FDA approved Amgen's Lumakras in May for treatment of patients with KRAS-G12C-mutated non-small cell lung cancer.[82] In June, Amgen and Kyowa Kirin announced joint plans to develop and commercialize a treatment for atopic dermatitis.[83]
  • Add to end of "2021" bullet:
In October, Amgen and Neumora Therapeutics announced a research and development collaboration focused on novel precision therapies for certain brain diseases.[84][85] Amgen began construction on a new biomanufacturing plant in New Albany, Ohio, in November.[86] In December, the FDA approved Amgen and AstraZeneca's Tezspire (tezepelumab) for severe asthma.[87] The FDA also approved Amgen's Otezla for adults with plaque psoriasis of any severity level.[88]
  • Add to beginning of "2022" bullet:
In January, Amgen announced a research collaboration with Generate Biomedicines across multiple modalities and several therapeutic areas for up to $1.9 billion.[89][90] The company also launched a multi-target collaboration with Arrakis Therapeutics to identify novel targeted RNA degrader therapeutics.[91][92] The next month, Amgen entered a multi-year collaboration with Plexium to discover novel targeted protein degradation therapies.[93][94] Also in February, Amgen issued its first green bond to fund various environmentally friendly initiatives across the company.[95][96] The company broke ground on a new manufacturing facility in Holly Springs, North Carolina, in March.[7][97]

Acquisition history

[edit]

Add:

    • Otezla (apremilast) (Acq 2019)[98]
    • Rodeo Therapeutics Corporation (Acq 2021)[99]
    • Five Prime Therapeutics (Acq 2021)[100]
    • ChemoCentryx (Acq 2021)[101]

Products

[edit]
  • Add where alphabetically appropriate:

Pipeline and clinical trials

[edit]
  • Update
In December 2013, Amgen had 11 drugs in Phase III clinical trials.[103]
to
As of August 2022, Amgen had 17 clinical programs underway in Phase III, eight in Phase II, and 19 in Phase I.[104]
  • I think it makes sense to move all the info from November 2014 and March 2015 to the Timeline section, since those candidates are no longer in the pipeline. Since Aimovig's approval is mentioned earlier in the article, it might make sense to just delete it from here as well.
In August 2020, Amgen, Takeda, and AbbVie, as part of a COVID-19 research and development (R&D) alliance, announced the first patients enrolled in the I-SPY COVID clinical trial. The trial evaluated the efficacy of Otezla and two other medicines in severely ill, hospitalized COVID-19 patients who required high-flow oxygen.[105]
In October 2020, Amgen announced positive topline Phase 2 results from the CodeBreaK 100 clinical study, evaluating sotorasib in 126 patients with KRAS G12C-mutant advanced NSCLC who had failed three or fewer prior lines of anti-cancer therapies (including immunotherapy and/or chemotherapy).[106] Amgen, the Global Coalition for Adaptive Research, and Eisai Co., Ltd. also announced enrollment of the first patient in a study testing multiple interventions for the treatment of patients hospitalized with COVID-19.[107][108]
In November 2020, Amgen, Takeda, and UCB, as part of the COVID R&D alliance, announced the first patient enrolled in another trial evaluating Otezla and two other drugs as treatments for COVID-19.[109] Amgen also announced that it would terminate its collaboration with Cytokinetics and transition the development and commercialization rights for omecamtiv mecarbil and AMG 594.[110] Amgen and AstraZeneca announced positive topline results from a Phase 3 trial in which the investigational medicine tezepelumab demonstrated a statistically significant reduction in exacerbations in patients with severe asthma.[111]
In December 2020, the FDA granted breakthrough therapy designation to sotorasib for advanced or metastatic non-small cell lung cancer patients with KRAS G12C mutation.[112]

References

  1. ^ http://www.toaks.org/home/showdocument?id=17130 (Page 162).
  2. ^ a b Cite error: The named reference Baker, Pam 2002 Page 37 was invoked but never defined (see the help page).
  3. ^ "Biotech giant Amgen has big plans for new plant". Moorpark Acorn. 16 February 2018.
  4. ^ Biasotti, Tony (9 April 2022). "In Thousand Oaks, biotech execs discuss industry's 'rising tide,' lament area's lack of housing". Pacific Coast Business Times. Retrieved 19 September 2022.
  5. ^ "Annual Comprehensive Financial Report". City of Thousand Oaks, California. 30 June 2021. p. 156. Retrieved 19 September 2022.
  6. ^ "Biotech giant Amgen has big plans for new plant". Moorpark Acorn. 16 February 2018.
  7. ^ a b Talhelm, Matt (7 March 2022). "Amgen to offer workers an average salary of $119,510 at new facility". WRAL TechWire. Retrieved 20 September 2022.
  8. ^ "Form 10-K". U.S. Securities and Exchange Commission.
  9. ^ Bidwell, Carol A. (1989). The Conejo Valley: Old and New Frontiers. Windsor Publications. Pages 128–129. ISBN 9780897812993.
  10. ^ Blankenship, Kyle (27 July 2020). "The top 20 drugs by global sales in 2019". Fierce Pharma. Retrieved 12 July 2022.
  11. ^ Hagen, Tony (4 February 2021). "Amgen Profits Get a Ride on Biosimilar Growth". The Center For Biosimilars. Retrieved 12 July 2022.
  12. ^ "AMGEN TOUR OF CALIFORNIA". Amgen Tour of California. Archived from the original on 2020-02-04. Retrieved 2020-02-07.
  13. ^ a b Walsh, Robin (27 October 2010). "A history of: Amgen". pharmaphorum.com. Retrieved 10 August 2022.
  14. ^ "Small Company Initial Public Offerings: June 1983". Inc.com. 1 September 1983. Retrieved 10 August 2022.
  15. ^ Ward, Nicholas (21 April 2019). "Amgen: This Beaten Down Blue Chip Is Priced To Own". TheStreet. Retrieved 10 August 2022.
  16. ^ Timmerman, Luke (13 May 2002). "Shrewd science: Biotech giant Amgen's success reflects its savvy corporate style". The Seattle Times. Retrieved 10 August 2022.
  17. ^ Bate, James (2 June 1989). "Biotech Detective Scores Coup : Amgen scientist spent years searching for the key to producing EPO". Los Angeles Times. Retrieved 10 August 2022.
  18. ^ a b Kim, Rachel (2019). Economics and management in the biopharmaceutical industry in the USA : evolution and strategic change. London: Routledge. pp. 2002–2003. ISBN 9781351012690. Retrieved 10 August 2022.
  19. ^ "Kirin and Amgen Hormone Venture". The New York Times. Reuters. 15 June 1984. Retrieved 10 August 2022.
  20. ^ Murphy, Barbara (20 May 1997). "Souza to Run Research at Biotech King Amgen". Los Angeles Times. Retrieved 10 August 2022.
  21. ^ Bendall, Linda J.; Bradstock, Kenneth F. (August 2014). "G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent". Cytokine & Growth Factor Reviews. 25 (4): 355–367. doi:10.1016/j.cytogfr.2014.07.011. Retrieved 10 August 2022.
  22. ^ "Gordon M. Binder, chief executive of Amgen..." Los Angeles Times. 17 October 1995. Retrieved 10 August 2022.
  23. ^ a b "Drugs@FDA: FDA Approved Drug Products".
  24. ^ "Amgen and its erythropoietin drugs". The Washington Post. 19 July 2012. Retrieved 20 September 2022.
  25. ^ Spencer, Dina (26 Sep 2019). "5 Top Pharma Manufacturers in Puerto Rico". PharmaBoardroom. Retrieved 10 August 2022.
  26. ^ Nathans, Aaron (16 September 1994). "Amgen, Phone Entrepreneur Win Medal of Technology". Los Angeles Times. Retrieved 10 August 2022.
  27. ^ "A Biotech Wonder Grows Up". Forbes. 3 Sep 2001. Retrieved 10 August 2022.
  28. ^ Hemp, Paul (1 July 2004). "A Time for Growth: An Interview with Amgen CEO Kevin Sharer". Harvard Business Review. Retrieved 10 August 2022.
  29. ^ Pollack, Andrew (19 September 2001). "F.D.A. Approves New Version of Amgen Drug". The New York Times. Retrieved 10 August 2022.
  30. ^ "FDA approves Amgen's new-generation filgrastim product, Neulasta". www.thepharmaletter.com. 2 Nov 2002. Retrieved 10 August 2022.
  31. ^ Pollack, Andrew (17 July 2002). "Amgen Reports Its Takeover Of Immunex". The New York Times. Retrieved 10 August 2022.
  32. ^ "New FDA Approvals". Relias Media. 1 May 2004. Retrieved 10 August 2022.
  33. ^ "Drug Approval Package: Sensipar (Cinacalcet HCI) NDA #021688". U.S. Food and Drug Administration. Retrieved 10 August 2022.
  34. ^ Gellene, Denise (30 March 2004). "Amgen to Buy Rival Tularik". Los Angeles Times. Retrieved 10 August 2022.
  35. ^ "Amgen buys remaining 79% of Tularik for $1.3B to boost R&D pipeline". The Pharma Letter. 4 April 2004. Retrieved 10 August 2022.
  36. ^ Pollack, Andrew (15 December 2005). "Amgen to Buy Abgenix, Getting Complete Control of New Colon Cancer Drug". The New York Times. Retrieved 10 August 2022.
  37. ^ Giusti, Ruthann M.; Shastri, Kaushikkumar A.; Cohen, Martin H.; Keegan, Patricia; Pazdur, Richard (May 2007). "FDA drug approval summary: panitumumab (Vectibix)". The Oncologist. 12 (5): 577–583. doi:10.1634/theoncologist.12-5-577. ISSN 1083-7159. Retrieved 10 August 2022.
  38. ^ Heavey, Susan (22 August 2008). "U.S. FDA approves Amgen's blood platelet booster". Reuters. Retrieved 10 August 2022.
  39. ^ Jamali, Faranak; Lemery, Steven; Ayalew, Kassa; Robottom, Suzanne; Robie-Suh, Kathy; Rieves, Dwaine; Pazdur, Richard (July 2009). "Romiplostim for the treatment of chronic immune (idiopathic) thrombocytopenic purpura". Oncology (Williston Park, N.Y.). 23 (8): 704–709. ISSN 0890-9091. Retrieved 10 August 2022.
  40. ^ "Amgen to buy Pfizer plant". The Irish Times. 11 March 2011. Retrieved 10 August 2022.
  41. ^ Timmerman, Luke (24 January 2011). "Xconomy: Amgen to Acquire BioVex for Up To $1B, to Obtain Cancer-Killing Virus Therapy". Xconomy. Retrieved 10 August 2022.
  42. ^ Dangi-Garimella, Surabhi (28 October 2015). "Cost Questions Will Follow the Approval of Amgen's Oncolytic Viral Treatment, Imlygic". AJMC. Retrieved 10 August 2022.
  43. ^ Pollack, Andrew (20 December 2011). "Amgen Plans to Team Up With Watson on Generics". The New York Times. Retrieved 10 August 2022.
  44. ^ "Amgen to buy Micromet for $1.2 billion". Reuters. 26 January 2012. Retrieved 10 August 2022.
  45. ^ "Amgen appoints CEO Robert Bradway to chair of board". PMLive. 17 December 2012. Retrieved 10 August 2022.
  46. ^ Writer, GEN Staff (25 April 2012). "Amgen Ponies Up $700M for Turkey's Mustafa Nevzat". GEN - Genetic Engineering and Biotechnology News. Retrieved 10 August 2022.
  47. ^ "Amgen to Pick Up Peptide Drug Firm KAI Pharmaceuticals for $315M". GEN - Genetic Engineering and Biotechnology News. 10 April 2012.
  48. ^ Taylor, Phil (8 February 2017). "Amgen's chronic kidney disease drug Parsabiv cleared in US". PMLive. Retrieved 11 August 2022.
  49. ^ "Amgen Buys deCODE Genetics for $415M". GEN - Genetic Engineering and Biotechnology News. 10 December 2012.
  50. ^ Becker, Zoey (27 June 2022). "Amgen partners with Fosun to bring Otezla, Parsabiv to patients in China". Fierce Pharma.
  51. ^ Philippidis, Alex (1 November 2019). "Amgen Expands China Presence, Cancer R&D with $2.7B BeiGene Collaboration". GEN - Genetic Engineering and Biotechnology News. Retrieved 11 August 2022.
  52. ^ Wright, Rob (27 Aug 2018). "Amgen's Acquisition Of Onyx Pharmaceuticals — Through The Eyes Of Tony Coles". Life Science Leader. Retrieved 11 August 2022.
  53. ^ Brennan, Zachary (21 November 2014). "Amgen launches $200m biomanufacturing facility in Singapore". BioPharma-Reporter. Retrieved 11 August 2022.
  54. ^ Przepiorka, Donna; Ko, Chia-Wen; Deisseroth, Albert; Yancey, Carolyn L.; Candau-Chacon, Reyes; Chiu, Haw-Jyh; Gehrke, Brenda J.; Gomez-Broughton, Candace; Kane, Robert C.; Kirshner, Susan; Mehrotra, Nitin; Ricks, Tiffany K.; Schmiel, Deborah; Song, Pengfei; Zhao, Ping; Zhou, Qing; Farrell, Ann T.; Pazdur, Richard (15 September 2015). "FDA Approval: Blinatumomab". Clinical Cancer Research: An Official Journal of the American Association for Cancer Research. 21 (18): 4035–4039. doi:10.1158/1078-0432.CCR-15-0612. ISSN 1557-3265. Retrieved 11 August 2022.
  55. ^ "FDA Approves Blinatumomab to Treat Rare Form of Acute Lymphoblastic Leukemia". The ASCO Post. 15 December 2014. Retrieved 11 August 2022.
  56. ^ Kolata, Gina (27 August 2015). "F.D.A. Approves Repatha, a Second Drug for Cholesterol in a Potent New Class". The New York Times. Retrieved 11 August 2022.
  57. ^ Tontonoz, Matthew. "T-VEC is First FDA-Approved Oncolytic Virus Therapy". Cancer Research Institute. Retrieved 11 August 2022.
  58. ^ a b Staton, Tracy (23 September 2016). "Amgen's Humira biosim, Amjevita, passes FDA milestone on long road to market". Fierce Pharma. Retrieved 11 August 2022.
  59. ^ Bell, Jacob (8 February 2017). "Amgen secures FDA approval for hormone drug". BioPharma Dive. Retrieved 11 August 2022.
  60. ^ a b "FDA approves bevacizumab biosimilar Mvasi". GaBI Online. 22 September 2017. Retrieved 11 August 2022.
  61. ^ Vuocolo, Alex (23 June 2020). "Khan Academy Founder Says $3M Grant Will Help Tackle Inequities in Virtual Education". Cheddar News. Retrieved 11 August 2022.
  62. ^ D'Angelo, Alexa (29 October 2017). "Amgen Foundation awards Khan Academy $3 million to support development of biology". Ventura County Star. Retrieved 11 August 2022.
  63. ^ Raedler, Lisa A. (15 April 2019). "Aimovig (Erenumab-aooe) First CGRP Receptor Antagonist Approved for the Prevention of Migraine in Adults". American Health & Drug Benefits. 12. Retrieved 11 August 2022.
  64. ^ "Amgen's New Bio-manufacturing Plant, Rhode Island, US". Pharmaceutical Technology. 10 August 2018. Retrieved 11 August 2022.
  65. ^ "Evenity gets first ever approval, in Japan". The Pharma Letter. 9 January 2019. Retrieved 11 August 2022.
  66. ^ Taylor, Phil (9 January 2019). "Amgen gets first OK for Evenity in Japan as FDA panel looms". Fierce Biotech. Retrieved 11 August 2022.
  67. ^ Liu, Angus (10 April 2019). "Amgen bone drug Evenity finally wins its FDA green light, but there's a catch". Fierce Pharma. Retrieved 11 August 2022.
  68. ^ a b "FDA Approves Amgen's Trastuzumab Biosimilar, Kanjinti". The Center For Biosimilars. 13 June 2019. Retrieved 11 August 2022.
  69. ^ "FDA approves Avsola, fourth Remicade biosimilar". www.healio.com. 6 Dec 2019. Retrieved 11 August 2022.
  70. ^ Kelly, Rhea (24 January 2020). "Amgen and Harvard Launch Free Online Science Ed Platform -- Campus Technology". Campus Technology. Retrieved 11 August 2022.
  71. ^ Kahn, Natalie L.; Wang, Andy Z. (8 April 2020). "Harvard's LabXChange Provides Platform for Remote Scientific Learning During Pandemic | News | The Harvard Crimson". The Harvard Crimson. Retrieved 11 August 2022.
  72. ^ "Amgen, AT&T, Others Announce Commitments for COVID-19 Response". Philanthropy News Digest. 25 March 2020. Retrieved 20 September 2022.
  73. ^ "BRIEF-Amgen Establishes Wholly-Owned Affiliate In Japan". Reuters. 1 April 2020. Retrieved 11 August 2022.
  74. ^ Liu, Angus (23 January 2020). "Amgen wades deeper into Asia with full control of an Astellas Japanese JV". Fierce Pharma. Retrieved 11 August 2022.
  75. ^ "Amgen defeats Novartis appeal over arthritis drug Enbrel's patents". Reuters. 1 July 2020. Retrieved 11 August 2022.
  76. ^ "Amgen Foundation awards $3 million to Khan Academy". Philanthropy News Digest. 24 July 2020. Retrieved 20 September 2022.
  77. ^ Molina, Brett (30 July 2020). "Q&A: Khan Academy CEO Sal Khan on the new school year and virtual learning". USA Today. Retrieved 20 September 2022.
  78. ^ Stevens, Pippa (24 August 2020). "Salesforce, Amgen and Honeywell added to Dow in major shake-up to the average". CNBC. Retrieved 11 August 2022.
  79. ^ Blankenship, Kyle (17 September 2020). "Eli Lilly, Amgen join forces to scale production of COVID-19 antibody cocktails". Fierce Pharma. Retrieved 11 August 2022.
  80. ^ Manfredi, Lucas (18 January 2021). "CEOs are driving an initiative to hire, train 1M Black workers over next 10 years". FOXBusiness. Retrieved 11 August 2022.
  81. ^ a b "FDA Approves Riabni, Third Biosimilar to Rituxan". Clinical Oncology News. 18 December 2020. Retrieved 20 September 2022.
  82. ^ a b ASCO Post Staff (June 25, 2021). "FDA Approves Sotorasib for KRAS G12C–Mutated NSCLC". ASCO Post. Retrieved March 4, 2022.
  83. ^ Idrus, Amirah Al (1 June 2021). "Amgen reunites with longtime partner Kyowa Kirin in $400M dermatitis deal". Fierce Biotech. Retrieved 20 September 2022.
  84. ^ Taylor, Nick Paul (7 October 2021). "Meet Neumora, Arch's $500M, Amgen-partnered play for the targeted future of neuroscience R&D". Fierce Biotech. Retrieved 20 September 2022.
  85. ^ "Amgen to invest $100 million in SoftBank-backed Neumora". Reuters. 7 October 2021. Retrieved 20 September 2022.
  86. ^ "Amgen breaks ground on new biomanufacturing facility in Ohio, US". NS Healthcare. 8 November 2021. Retrieved 20 September 2022.
  87. ^ a b Dunleavy, Kevin (20 December 2021). "Amgen, AstraZeneca score FDA nod for blockbuster hopeful asthma drug Tezspire". Fierce Pharma. Retrieved 20 September 2022.
  88. ^ "U.S. FDA approves expanded use of Amgen's psoriasis drug". Reuters. 20 December 2021. Retrieved 20 September 2022.
  89. ^ Armstrong, Annalee (6 January 2022). "Amgen chooses Generate in $1.9B biobucks deal to churn out up to 10 multispecific drugs". Fierce Biotech. Retrieved 23 September 2022.
  90. ^ Philippidis, Alex (6 January 2022). "Amgen, Generate Launch Up-to-$1.9B Protein Therapeutics Collaboration". GEN - Genetic Engineering and Biotechnology News. Retrieved 23 September 2022.
  91. ^ Armstrong, Annalee (11 January 2022). "JPM 2022: Amgen teams up with Arrakis to destroy disease-causing RNA in $75M research deal". Fierce Biotech. Retrieved 23 September 2022.
  92. ^ Pagliarulo, Ned (11 January 2022). "Amgen partners with Arrakis to develop drugs aimed at RNA". BioPharma Dive. Retrieved 23 September 2022.
  93. ^ Shasteen, Hayley (3 February 2022). "Amgen and Plexium Ink $500M Targeted Protein Degradation Therapies Pact". BioSpace. Retrieved 23 September 2022.
  94. ^ LaHucik, Kyle (3 February 2022). "Amgen enters hot protein degradation field with $500M biobucks deal with Plexium". Fierce Biotech. Retrieved 23 September 2022.
  95. ^ Pequeño IV, Antonio (23 February 2022). "Amgen Issues 'Green Bond'". San Fernando Valley Business Journal. Retrieved 23 September 2022.
  96. ^ Mutua, David Caleb (29 March 2022). "Amgen Mulls More Green Bonds After 'Robust Interest' in Debut". www.bloomberg.com. Retrieved 23 September 2022.
  97. ^ Sterling, John (11 March 2022). "Amgen Breaks Ground on NC Biomanufacturing Facility". GEN - Genetic Engineering and Biotechnology News. Retrieved 23 September 2022.
  98. ^ Erman, Michael; Mishra, Manas (26 August 2019). "Amgen to buy Celgene psoriasis drug Otezla for $13.4 billion". Reuters. Retrieved 23 September 2022.
  99. ^ Idrus, Amirah Al (30 March 2021). "Amgen saddles up with Rodeo for a $55M trek into regenerative medicine". Fierce Biotech. Retrieved 23 September 2022.
  100. ^ Adams, Ben (4 March 2021). "Prime time for Five Prime as Amgen snaps up this once-moribund biotech for $1.9B and its phoenix-from-the-flames cancer asset". Fierce Biotech. Retrieved 23 September 2022.
  101. ^ Philippidis, Alex (5 August 2022). "Amgen to Acquire ChemoCentryx for $3.7B, Bolstering Autoimmune Portfolio". GEN - Genetic Engineering and Biotechnology News. Retrieved 23 September 2022.
  102. ^ Jeffries, Fleur (28 March 2022). "Amgen shares new Otezla data at American Academy of Dermatology congress 2022". PMLive. Retrieved 11 August 2022.
  103. ^ Amgen Phase III Pipeline Archived 2015-07-29 at the Wayback Machine, accessed December 29, 2013
  104. ^ "Amgen Pipeline". Amgen Pipeline. Retrieved 16 August 2022.
  105. ^ Liu, Angus (3 August 2020). "AbbVie, Amgen and Takeda test anti-inflammatory drugs in joint COVID-19 study". Fierce Pharma.
  106. ^ Helwick, Caroline (1 Feb 2021). "Phase II CodeBreak 100 Validates Early Benefit for KRAS Inhibitor in NSCLC". The ASCO Post. Retrieved 16 August 2022.
  107. ^ "Biotech Stock Roundup: GILD's Veklury Approved, NVAX Provides Vaccine Update & More". Yahoo Finance. 28 Oct 2020. Retrieved 16 August 2022.
  108. ^ Ross, Casey (10 November 2020). "Drug companies deliver a vote of confidence in adaptive trial for Covid-19". STAT. Retrieved 16 August 2022.
  109. ^ Beasley, Deena (30 November 2020). "COVID R&D Alliance launches trial of Amgen, UCB, Takeda drugs". Reuters. Retrieved 16 August 2022.
  110. ^ Gardner, Jonathan (23 Nov 2020). "Amgen cuts Cytokinetics loose after heart drug disappointment". BioPharma Dive. Retrieved 16 August 2022.
  111. ^ Dembeck, Lauren (18 October 2021). "NAVIGATOR Trial Outcomes for Tezepelumab Use in Severe, Uncontrolled Asthma". Pulmonology Advisor. Retrieved 16 August 2022.
  112. ^ Taylor, Nick Paul (8 December 2020). "Amgen plans 2020 filing for FDA approval of KRAS drug sotorasib". Fierce Biotech. Retrieved 16 August 2022.
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