|Jmol-3D images||Image 1
|Molar mass||228.18 g/mol|
|Appearance||white to yellowish crystals|
120 °C (393 K) decomp.
|Solubility in water||80 g/100 ml (25 °C)|
|EU classification||Oxidant (O)
|R-phrases||R8, R22, R36/37/38, R42/43|
|S-phrases||(S2), S22, S24, S26, S37|
|LD50||689 mg/kg, oral (rat)|
|Other anions||Ammonium thiosulfate
|Other cations||Sodium persulfate
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Ammonium persulfate (APS) (NH4)2S2O8 is a strong oxidizing agent. It is very soluble in water; the dissolution of the salt in water is endothermic. When APS dissolves in water, it is broken down into ammonia and peroxydisulfuric acid. It is a radical initiator. It is used to etch copper on printed circuit boards as an alternative to ferric chloride solution. It is also used along with tetramethylethylenediamine to catalyze the polymerization of acrylamide in making a polyacrylamide gel. In addition, a high ammonium persulfate solution can be used to leach copper from chalcopyrite under high pressure conditions. 
In 1908, John William Turrentine used a dilute ammonium persulfate solution to etch copper. Turrentine weighed copper spirals before placing the copper spirals into the ammonium persulfate solution for an hour. After an hour, the spirals were weighed again and the amount of copper dissolved by ammonium persulfate was recorded. This experiment was extended to other metals such as nickel, cadium, and iron, all of which yielded similar results. 
Ammonium persulfate is the main component of Nochromix. On dissolving in sulfuric acid, it is used to clean laboratory glassware as a metal-free alternative to chromic acid baths. It is also a standard ingredient in western blot gels and hair bleach.
It has been noted that persulfate salts are a major cause of asthmatic effects in women.  Furthermore, it has been suggested that exposure to ammonium persulfate can cause asthmatic effects in hair dressers and receptionists working in the hair dressing industry. These asthmatic affects are proposed to be caused by the oxidation of cysteine residues, as well as methionine residues.
- "Ammonium Persulphate: Copper Etchant". MG Chemicals.
- Turan, M; Altundoğan, H. S. (2013). "Leaching of copper from chalcopyrite concentrate by using ammonium persulphate in an autoclave: Determination of most suitable impeller type by using response surface methodology.". Journal of Central South University 20: 622–628.
- Hugh Marshall (1891). "LXXIV. Contributions from the Chemical Laboratory of the University of Edinburgh. No. V. The persulphates". J. Chem. Soc., Trans. 59: 771. doi:10.1039/CT8915900771.
- Turrentine, J. W. (1908). "Action of Ammonium Persulphate on Metals.". Journal of Physical Chemistry 11: 623–631.
- "Nochromix". Sigma-Aldrich. Retrieved 2008-03-01.[dead link]
-  FMC Corporation, MSDS sheet dated: 06/26/2009
- De Vooght, V.; Jesus Cruz, M.; Haenen, S.; Wijnhoven, K.; Munoz, X.; Cruz, M.; Munoz, X.; Morell, F.; Nemery, B (2010). "Ammonium persulfate can initiate an asthmatic response in mice.". Thorax 65: 252–257.
- Pignatti, P.; Frossi, B.; Pala, G.; Negri, S.; Oman, H.; Perfetti, L.; Pucillo, C.; Imbriani, M.; Moscato, G. (2013). "Oxidative activity of ammonium persulfate salt on mast cells and basophils: implication in hairdressers' asthma.". Int. Arch. Allergy Immunol. 160: 409–419.
For a review of its uses in organic chemistry see Encyclopedia of Reagents for Organic Synthesis, vol. 1, pp. 193–197(1995).