FKBP10

FKBP10
Identifiers
Aliases	FKBP10, FKBP65, OI11, OI6, PPIASE, hFKBP65, BRKS1, FK506 binding protein 10, FKBP prolyl isomerase 10
External IDs	OMIM: 607063; MGI: 104769; HomoloGene: 7718; GeneCards: FKBP10; OMA:FKBP10 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	41,823,213 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,315,650 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; ascending aorta; ; anterior pituitary; ; right coronary artery; ; canal of the cervix; ; left coronary artery; ; left uterine tube; ; gallbladder; ; right adrenal gland; ; smooth muscle tissue;
	Top expressed in
	calvaria; ; internal carotid artery; ; external carotid artery; ; body of femur; ; fossa; ; molar; ; vas deferens; ; dermis; ; condyle; ; ascending aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; metal ion binding; FK506 binding;
Cellular component	endoplasmic reticulum lumen; endoplasmic reticulum; cytoplasm; nucleolus;
Biological process	chaperone-mediated protein folding; histone peptidyl-prolyl isomerization; peptidyl-proline modification; protein peptidyl-prolyl isomerization;
	Sources:Amigo / QuickGO
Orthologs
	60681
	14230
	ENSG00000141756
	ENSMUSG00000001555
	Q96AY3
	Q61576
	NM_021939
	NM_001163481; NM_010221
	NP_068758
	NP_001156953; NP_034351
	Wikidata
View/Edit Human	View/Edit Mouse

FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141756 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001555 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Patterson CE, Schaub T, Coleman EJ, Davis EC (Feb 2001). "Developmental Regulation of FKBP65: An ER-localized Extracellular Matrix Binding-Protein". Mol Biol Cell. 11 (11): 3925–35. doi:10.1091/mbc.11.11.3925. PMC 15047. PMID 11071917.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ Ishikawa Y, Vranka J, Wirz J, Nagata K, Bachinger HP (Nov 2008). "The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens". J Biol Chem. 283 (46): 31584–90. doi:10.1074/jbc.M802535200. PMID 18786928.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: FKBP10 FK506 binding protein 10, 65 kDa".

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)