FKBP8

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FK506 binding protein 8, 38kDa
Protein FKBP8 PDB 2awg.png
PDB rendering based on 2awg.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols FKBP8 ; FKBP38; FKBPr38
External IDs OMIM604840 MGI1341070 HomoloGene7720 GeneCards: FKBP8 Gene
EC number 5.2.1.8
RNA expression pattern
PBB GE FKBP8 40850 at tn.png
PBB GE FKBP8 208255 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23770 14232
Ensembl ENSG00000105701 ENSMUSG00000019428
UniProt Q14318 O35465
RefSeq (mRNA) NM_012181 NM_001111066
RefSeq (protein) NP_036313 NP_001104536
Location (UCSC) Chr 19:
18.64 – 18.65 Mb
Chr 8:
70.53 – 70.54 Mb
PubMed search [1] [2]

FK506-binding protein 8 is a protein that in humans is encoded by the FKBP8 gene.[1][2]

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.[2]

References[edit]

  1. ^ Lam E, Martin M, Wiederrecht G (Sep 1995). "Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs". Gene 160 (2): 297–302. doi:10.1016/0378-1119(95)00216-S. PMID 7543869. 
  2. ^ a b "Entrez Gene: FKBP8 FK506 binding protein 8, 38kDa". 

Further reading[edit]