Foster Kennedy syndrome
|Foster Kennedy syndrome|
|Classification and external resources|
Pseudo-Foster Kennedy syndrome is defined as one-sided optic atrophy with papilledema in the other eye but with the absence of a mass.
The syndrome is defined as the following changes:
- optic atrophy in the ipsilateral eye
- disc edema in the contralateral eye
- Central scotoma (loss of vision in the middle of the visual fields) in the ipsilateral eye
- anosmia (loss of smell) ipsilaterally
This syndrome is due to optic nerve compression, olfactory nerve compression, and increased intracranial pressure (ICP) secondary to a mass (such as meningioma or plasmacytoma, usually an olfactory groove meningioma). There are other symptoms present in some cases such as nausea and vomiting, memory loss and emotional lability (i.e. frontal lobe signs).
The syndrome was first extensively noted by Robert Foster Kennedy in 1911, a British neurologist, who spent most of his career working in the United States of America. However, the first mention of the syndrome came from a William Gowers in 1893. Schultz-Zehden described the symptoms again in 1905. A later description was written by Wilhelm Uhthoff in 1915.
Treatment and prognosis
The treatment, and therefore prognosis, varies depending upon the underlying tumour.
- "Kennedy syndrome" at Dorland's Medical Dictionary
- "Foster Kennedy syndrome" at Dorland's Medical Dictionary
- Bansal S, Dabbs T, Long V (2008). "Pseudo-Foster Kennedy Syndrome due to unilateral optic nerve hypoplasia: a case report". J Med Case Reports 2: 86. doi:10.1186/1752-1947-2-86. PMC 2278154. PMID 18348732. Retrieved 2008-08-13.
- Longmore, Murray; Ian Wilkinson, Tom Turmezei, Chee Kay Cheung (2007). Oxford Handbook of Clinicial Medicine, 7th edition. Oxford University Press. p. 690. ISBN 0-19-856837-1.
- Willacy, Hayley. "Foster Kennedy syndrome". Retrieved 2008-08-13.
- Thorofare, NJ (1911). Kennedy F; Retrobulbar neuritis as an exact diagnostic sign of certain tumors and abscesses in the frontal lobe. American Journal of the Medical Sciences.
- "Kennedy's syndrome". Retrieved 2008-08-13.