Paramethadione

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Paramethadione
Paramethadione.svg
Systematic (IUPAC) name
(RS)-5-ethyl-3,5-dimethyl-oxazolidine-2,4-dione
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
Pregnancy cat.
Legal status
?
Pharmacokinetic data
Protein binding Not significant
Identifiers
CAS number 115-67-3
ATC code N03AC01
PubChem CID 8280
DrugBank DB00617
ChemSpider 7979 YesY
UNII Z615FRW64N YesY
KEGG D00495 YesY
ChEMBL CHEMBL1100 YesY
Chemical data
Formula C7H11NO3 
Mol. mass 157.167 g/mol
 YesY (what is this?)  (verify)

Paramethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.[1]

Chemistry[edit]

Paramethadione, 5-ethyl-3,5-dimethyloxazolidine-2,4-dione, differs from trimethadione only in the substitution of one methyl group with an ethyl group. It is synthesized in a completely analogous manner, except that it comes from 2-hydroxy-2-methylbutyric acid instead of 2-hydroxyisobutyric acid.

References[edit]

External links[edit]