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Abbreviations PHMB
CAS number 28757-47-3 N, 32289-58-0 (HCl) YesY, 28757-48-4
UNII 322U039GMF YesY
ATC code D08AC05
Molecular formula (C8H17N5)n
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use[1] it is spelled polihexanide (INN) and sold under names such as Lavasept and Serasept.[2]

Some products containing PHMB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.[3]

Branded as Baquacil, it also has an application as a swimming-pool sanitizer in place of chlorine- or bromine-based products.

Polyhexanide is used as an ingredient in some eye drops for use with contact lenses.

See also[edit]


  1. ^ Ansorg R, Rath PM, Fabry W (2003). "Inhibition of the anti-staphylococcal activity of the antiseptic polihexanide by mucin". Arzneimittel-Forschung 53 (5): 368–71. doi:10.1055/s-0031-1297121. PMID 12854364. 
  2. ^ International Drug Names: Polihexanide
  3. ^ Nusept