|cobicistat||cytochrome P450 inhibitor|
|tenofovir disoproxil fumarate||reverse-transcriptase inhibitor|
Elvitegravir/cobicistat/emtricitabine/tenofovir (brand name Stribild), also known as the Quad pill, is a fixed dose combination drug for the treatment of HIV/AIDS. Elvitegravir, emtricitabine and tenofovir directly suppress viral reproduction. Cobicistat increases the effectiveness of the combination by inhibiting the liver and gut wall enzymes that metabolize elvitegravir.
The drug is manufactured by Gilead Sciences. Stribild gained approval by U.S. Food and Drug Administration on August 27, 2012 for use in adult patients starting antiretroviral treatment for the first time as part of the fixed dose combination.
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