Onchidal: Difference between revisions

Onchidal
Clinical data
ATC code	none;
Identifiers
	IUPAC name (1E,3E)- 5-(2,2-dimethyl- 6-methylenecyclohexyl)- 3-formylpenta- 1,3-dien- 1-yl acetate;
CAS Number	67656-42-2;
PubChem CID	6441116;
CompTox Dashboard (EPA)	DTXSID90897204 ;
Chemical and physical data
Formula	C17H24O3
Molar mass	276.371 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)O\C=C\C(=C/CC1C(=C)CCCC1(C)C)\C=O;

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Revision as of 11:25, 31 July 2009

Onchidal is a naturally occurring toxin produced as a defensive secretion by the mollusc Onchidella binneyi and several other related species in the Onchidella genus. It acts as an irreversible acetylcholinesterase inhibitor, the same mechanism of action as that of the deadly nerve agents, however onchidal is not an organophosphorus or carbamate compound and bears little resemblance to other compounds of this nature.^[1]

^ Abramson SN, Radic Z, Manker D, Faulkner DJ, Taylor P. Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action. Molecular Pharmacology. 1989 Sep;36(3):349-54. PMID 2779521

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 '''Onchidal''' is a naturally occurring [[toxin]] produced as a defensive secretion by the [[mollusc]] ''[[Onchidella binneyi]]'' and several other related species in the ''[[Onchidella]]'' genus. It acts as an irreversible [[acetylcholinesterase inhibitor]], the same mechanism of action as that of the deadly [[nerve agent]]s, however onchidal is not an [[organophosphorus]] or [[carbamate]] compound and bears little resemblance to other compounds of this nature.<ref>Abramson SN, Radic Z, Manker D, Faulkner DJ, Taylor P. Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action. ''Molecular Pharmacology''. 1989 Sep;36(3):349-54. PMID 2779521</ref>
-{{Toxins}}
 == References ==
 <references />
+{{Toxins}}
 [[Category:Anticholinesterases]]
 [[Category:Toxins]]
 {{pharmacology-stub}}