HNRNPR: Difference between revisions

HNRNPR
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2DK2
Identifiers
Aliases	HNRNPR, HNRPR, hnRNP-R, heterogeneous nuclear ribonucleoprotein R
External IDs	OMIM: 607201; MGI: 1891692; HomoloGene: 4251; GeneCards: HNRNPR; OMA:HNRNPR - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	23,344,336 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	136,086,758 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; appendix; ; smooth muscle tissue; ; epithelium of colon; ; islet of Langerhans; ; rectum; ; monocyte; ; left ovary;
	Top expressed in
	ventricular zone; ; tail of embryo; ; genital tubercle; ; hand; ; neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; yolk sac; ; ganglionic eminence; ; embryo; ; Rostral migratory stream;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	mRNA 3'-UTR binding; nucleic acid binding; protein binding; RNA binding; mRNA binding;
Cellular component	nucleolus; cytoplasm; axon terminus; growth cone; nucleus; intracellular membrane-bounded organelle; dendrite; endoplasmic reticulum; catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; ribonucleoprotein complex;
Biological process	circadian rhythm; positive regulation of mRNA catabolic process; mRNA destabilization; negative regulation of catalytic activity; mRNA processing; mRNA splicing, via spliceosome; RNA splicing; RNA metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10236
	74326
	ENSG00000282958; ENSG00000125944
	ENSMUSG00000066037
	O43390
	n/a
NM_001102397; NM_001102398; NM_001102399; NM_001297620; NM_001297621;
	NM_001297622; NM_005826
	NM_001277121; NM_001277122; NM_001277123; NM_028871; NM_001355182
NP_001095867; NP_001095868; NP_001095869; NP_001284549; NP_001284550;
	NP_001284551; NP_005817
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

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Revision as of 17:09, 11 December 2020

Heterogeneous nuclear ribonucleoprotein R is a protein that in humans is encoded by the HNRNPR gene.^[5]^[6]

Function

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif.^[6]

Interactions

HNRNPR has been shown to interact with SMN1^[7]^[8] and PRMT1.^[9]^[10]

Role in disease

References

^ ^a ^b ^c ENSG00000125944 GRCh38: Ensembl release 89: ENSG00000282958, ENSG00000125944 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066037 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hassfeld W, Chan EK, Mathison DA, Portman D, Dreyfuss G, Steiner G, Tan EM (January 1998). "Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P". Nucleic Acids Research. 26 (2): 439–45. doi:10.1093/nar/26.2.439. PMC 147279. PMID 9421497.
^ ^a ^b "Entrez Gene: HNRPR heterogeneous nuclear ribonucleoprotein R".
^ Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G (October 2001). "SMN interacts with a novel family of hnRNP and spliceosomal proteins". The EMBO Journal. 20 (19): 5443–52. doi:10.1093/emboj/20.19.5443. PMC 125643. PMID 11574476.
^ Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M (January 2002). "Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?". Human Molecular Genetics. 11 (1): 93–105. doi:10.1093/hmg/11.1.93. PMID 11773003.
^ Wada K, Inoue K, Hagiwara M (August 2002). "Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1591 (1–3): 1–10. doi:10.1016/S0167-4889(02)00202-1. PMID 12183049.
^ Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070.

External links

HNRNPR human gene location in the UCSC Genome Browser.
HNRNPR human gene details in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: O43390 (Heterogeneous nuclear ribonucleoprotein R) at the PDBe-KB.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] ENSG00000125944 GRCh38: Ensembl release 89: ENSG00000282958, ENSG00000125944 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000066037 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9421497-5] Hassfeld W, Chan EK, Mathison DA, Portman D, Dreyfuss G, Steiner G, Tan EM (January 1998). "Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P". Nucleic Acids Research. 26 (2): 439–45. doi:10.1093/nar/26.2.439. PMC 147279. PMID 9421497.

[entrez-6] "Entrez Gene: HNRPR heterogeneous nuclear ribonucleoprotein R".

[pmid11574476-7] Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G (October 2001). "SMN interacts with a novel family of hnRNP and spliceosomal proteins". The EMBO Journal. 20 (19): 5443–52. doi:10.1093/emboj/20.19.5443. PMC 125643. PMID 11574476.

[pmid11773003-8] Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M (January 2002). "Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?". Human Molecular Genetics. 11 (1): 93–105. doi:10.1093/hmg/11.1.93. PMID 11773003.

[pmid12183049-9] Wada K, Inoue K, Hagiwara M (August 2002). "Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1591 (1–3): 1–10. doi:10.1016/S0167-4889(02)00202-1. PMID 12183049.

[pmid16169070-10] Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070.

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@@ Line 1: / Line 1: @@
 {{Infobox_gene}}
-'''Heterogeneous nuclear ribonucleoprotein R''' is a [[protein]] that in humans is encoded by the ''HNRNPR'' [[gene]].<ref name="pmid9421497">{{cite journal | vauthors = Hassfeld W, Chan EK, Mathison DA, Portman D, Dreyfuss G, Steiner G, Tan EM | title = Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P | journal = Nucleic Acids Research | volume = 26 | issue = 2 | pages = 439–45 | date = Jan 1998 | pmid = 9421497 | pmc = 147279 | doi = 10.1093/nar/26.2.439 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HNRPR heterogeneous nuclear ribonucleoprotein R| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10236| accessdate = }}</ref>
+'''Heterogeneous nuclear ribonucleoprotein R''' is a [[protein]] that in humans is encoded by the ''HNRNPR'' [[gene]].<ref name="pmid9421497">{{cite journal | vauthors = Hassfeld W, Chan EK, Mathison DA, Portman D, Dreyfuss G, Steiner G, Tan EM | title = Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P | journal = Nucleic Acids Research | volume = 26 | issue = 2 | pages = 439–45 | date = January 1998 | pmid = 9421497 | pmc = 147279 | doi = 10.1093/nar/26.2.439 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HNRPR heterogeneous nuclear ribonucleoprotein R| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10236| accessdate = }}</ref>
 == Function ==
@@ Line 8: / Line 8: @@
 == Interactions ==
-HNRNPR has been shown to [[Protein-protein interaction|interact]] with [[SMN1]]<ref name=pmid11574476>{{cite journal | vauthors = Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G | title = SMN interacts with a novel family of hnRNP and spliceosomal proteins | journal = The EMBO Journal | volume = 20 | issue = 19 | pages = 5443–52 | date = Oct 2001 | pmid = 11574476 | pmc = 125643 | doi = 10.1093/emboj/20.19.5443 }}</ref><ref name=pmid11773003>{{cite journal | vauthors = Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M | title = Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? | journal = Human Molecular Genetics | volume = 11 | issue = 1 | pages = 93–105 | date = Jan 2002 | pmid = 11773003 | doi = 10.1093/hmg/11.1.93 | doi-access = free }}</ref> and [[PRMT1]].<ref name=pmid12183049>{{cite journal | vauthors = Wada K, Inoue K, Hagiwara M | title = Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy | journal = Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | volume = 1591 | issue = 1–3 | pages = 1–10 | date = Aug 2002 | pmid = 12183049 | doi = 10.1016/S0167-4889(02)00202-1 }}</ref><ref name=pmid16169070>{{cite journal | vauthors = Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE | title = A human protein-protein interaction network: a resource for annotating the proteome | journal = Cell | volume = 122 | issue = 6 | pages = 957–68 | date = Sep 2005 | pmid = 16169070 | doi = 10.1016/j.cell.2005.08.029 | hdl = 11858/00-001M-0000-0010-8592-0 | hdl-access = free }}</ref>
+HNRNPR has been shown to [[Protein-protein interaction|interact]] with [[SMN1]]<ref name=pmid11574476>{{cite journal | vauthors = Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G | title = SMN interacts with a novel family of hnRNP and spliceosomal proteins | journal = The EMBO Journal | volume = 20 | issue = 19 | pages = 5443–52 | date = October 2001 | pmid = 11574476 | pmc = 125643 | doi = 10.1093/emboj/20.19.5443 }}</ref><ref name=pmid11773003>{{cite journal | vauthors = Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M | title = Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? | journal = Human Molecular Genetics | volume = 11 | issue = 1 | pages = 93–105 | date = January 2002 | pmid = 11773003 | doi = 10.1093/hmg/11.1.93 | doi-access = free }}</ref> and [[PRMT1]].<ref name=pmid12183049>{{cite journal | vauthors = Wada K, Inoue K, Hagiwara M | title = Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy | journal = Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | volume = 1591 | issue = 1–3 | pages = 1–10 | date = August 2002 | pmid = 12183049 | doi = 10.1016/S0167-4889(02)00202-1 }}</ref><ref name=pmid16169070>{{cite journal | vauthors = Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE | title = A human protein-protein interaction network: a resource for annotating the proteome | journal = Cell | volume = 122 | issue = 6 | pages = 957–68 | date = September 2005 | pmid = 16169070 | doi = 10.1016/j.cell.2005.08.029 | hdl = 11858/00-001M-0000-0010-8592-0 | hdl-access = free }}</ref>
+== Role in disease ==
 == References ==
@@ Line 14: / Line 18: @@
 == Further reading ==
-{{refbegin|33em}}
+{{Refbegin | 2}}
-* {{cite journal | vauthors = Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G | title = SMN interacts with a novel family of hnRNP and spliceosomal proteins | journal = The EMBO Journal | volume = 20 | issue = 19 | pages = 5443–52 | date = Oct 2001 | pmid = 11574476 | pmc = 125643 | doi = 10.1093/emboj/20.19.5443 }}
+* {{cite journal | vauthors = Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G | title = SMN interacts with a novel family of hnRNP and spliceosomal proteins | journal = The EMBO Journal | volume = 20 | issue = 19 | pages = 5443–52 | date = October 2001 | pmid = 11574476 | pmc = 125643 | doi = 10.1093/emboj/20.19.5443 }}
-* {{cite journal | vauthors = Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M | title = Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? | journal = Human Molecular Genetics | volume = 11 | issue = 1 | pages = 93–105 | date = Jan 2002 | pmid = 11773003 | doi = 10.1093/hmg/11.1.93 | doi-access = free }}
+* {{cite journal | vauthors = Rossoll W, Kröning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M | title = Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? | journal = Human Molecular Genetics | volume = 11 | issue = 1 | pages = 93–105 | date = January 2002 | pmid = 11773003 | doi = 10.1093/hmg/11.1.93 | doi-access = free }}
-* {{cite journal | vauthors = Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ | title = Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis | journal = RNA | volume = 8 | issue = 4 | pages = 426–39 | date = Apr 2002 | pmid = 11991638 | pmc = 1370266 | doi = 10.1017/S1355838202021088 }}
+* {{cite journal | vauthors = Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ | title = Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis | journal = RNA | volume = 8 | issue = 4 | pages = 426–39 | date = April 2002 | pmid = 11991638 | pmc = 1370266 | doi = 10.1017/S1355838202021088 }}
-* {{cite journal | vauthors = Wada K, Inoue K, Hagiwara M | title = Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy | journal = Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | volume = 1591 | issue = 1–3 | pages = 1–10 | date = Aug 2002 | pmid = 12183049 | doi = 10.1016/S0167-4889(02)00202-1 }}
+* {{cite journal | vauthors = Wada K, Inoue K, Hagiwara M | title = Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy | journal = Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | volume = 1591 | issue = 1–3 | pages = 1–10 | date = August 2002 | pmid = 12183049 | doi = 10.1016/S0167-4889(02)00202-1 }}
-* {{cite journal | vauthors = Angenstein F, Evans AM, Settlage RE, Moran ST, Ling SC, Klintsova AY, Shabanowitz J, Hunt DF, Greenough WT | title = A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons | journal = The Journal of Neuroscience | volume = 22 | issue = 20 | pages = 8827–37 | date = Oct 2002 | pmid = 12388589 | pmc = 6757688 | doi =  10.1523/jneurosci.22-20-08827.2002}}
+* {{cite journal | vauthors = Angenstein F, Evans AM, Settlage RE, Moran ST, Ling SC, Klintsova AY, Shabanowitz J, Hunt DF, Greenough WT | title = A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons | journal = The Journal of Neuroscience | volume = 22 | issue = 20 | pages = 8827–37 | date = October 2002 | pmid = 12388589 | pmc = 6757688 | doi =  10.1523/jneurosci.22-20-08827.2002}}
 * {{cite journal | vauthors = Hassel S, Eichner A, Yakymovych M, Hellman U, Knaus P, Souchelnytskyi S | title = Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry | journal = Proteomics | volume = 4 | issue = 5 | pages = 1346–58 | date = May 2004 | pmid = 15188402 | doi = 10.1002/pmic.200300770 }}
-* {{cite journal | vauthors = Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M | title = Nucleolar proteome dynamics | journal = Nature | volume = 433 | issue = 7021 | pages = 77–83 | date = Jan 2005 | pmid = 15635413 | doi = 10.1038/nature03207 }}
+* {{cite journal | vauthors = Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M | title = Nucleolar proteome dynamics | journal = Nature | volume = 433 | issue = 7021 | pages = 77–83 | date = January 2005 | pmid = 15635413 | doi = 10.1038/nature03207 }}
 * {{cite journal | vauthors = Huang J, Chen XH, Wu K, Xu P | title = Cloning and expression of a novel isoform of heterogeneous nuclear ribonucleoprotein-R | journal = NeuroReport | volume = 16 | issue = 7 | pages = 727–30 | date = May 2005 | pmid = 15858414 | doi = 10.1097/00001756-200505120-00014 }}
-* {{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Research | volume = 16 | issue = 1 | pages = 55–65 | date = Jan 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }}
+* {{cite journal | vauthors = Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S | title = Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes | journal = Genome Research | volume = 16 | issue = 1 | pages = 55–65 | date = January 2006 | pmid = 16344560 | pmc = 1356129 | doi = 10.1101/gr.4039406 }}
-* {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
+* {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | date = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
-* {{cite journal | vauthors = Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M | title = Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns | journal = Genome Biology | volume = 8 | issue = 8 | pages = R154 | year = 2007 | pmid = 17672918 | pmc = 2374985 | doi = 10.1186/gb-2007-8-8-r154 }}
+* {{cite journal | vauthors = Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M | title = Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns | journal = Genome Biology | volume = 8 | issue = 8 | pages = R154 | date = 2007 | pmid = 17672918 | pmc = 2374985 | doi = 10.1186/gb-2007-8-8-r154 }}
+* {{cite journal | vauthors = Briese M, Saal-Bauernschubert L, Ji C, Moradi M, Ghanawi H, Uhl M, Appenzeller S, Backofen R, Sendtner M | title = hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 115 | issue = 12 | pages = E2859-68 | date = March 2018 | pmid = 29507242 | doi = 10.1073/pnas.1721670115 | issn = 1091-6490 | doi-access = free }}
 {{refend}}

v t e RNA-binding protein: Ribonucleoproteins
snRNP	A A1 B B2 C D1 D2 D3 E F G N 70K/U1 spliceosomal RNA SNRNP200
hnRNP	A0 C L R
Other transcription	Telomerase
Translation	Ribosome
Vault ribonucleoprotein particles	Major vault protein
Other	Signal recognition particle