Board of Radiation and Isotope Technology in short known as "BRIT" is a constituent unit under the Department of Atomic Energy[1] with its headquarters in Navi Mumbai, India.[2] It is involved in production, development, and supply of radioisotope based products and provision of isotope applications, radiation processing, radioanalytical services etc. It has regional centres at Rawatbhatta-Kota in Rajasthan,Bengaluru in Karnataka, Delhi, Hyderabad in Andhra Pradesh, Kolkata in West Bengal and Dirugarh in Assam. It has about 600 employees.[3]
Labelled Compounds - BRIT Vashi Complex
BRIT previously operated under the aegis of the Bhabha Atomic Research Centre before being made into a separate entity; however BRIT's name remains synonymous with BARC, as strong ties continue to exist between the two organizations, including collaborations on a variety of projects, sharing of office campuses, etc.
Inaguration of Test Facility by Dr. Anil Kakodkar & Dr. A. K. Kohli
It produces and supply a variety of radioisotope products including radioisotope generators, sealed radiation sources, radiochemicals, labelled compounds of carbon-14, tritium and sulphur-35 and nucleotides labelled with phosphorus-32, radiopharmaceuticals and RIA kits, gamma radiography equipment and gamma laboratory irradiator systems to users in the country and abroad. Range of sealed radiation sources include Co-60 irradiator and radiography sources, Ir-192 radiography sources and brachytherapy sources. BRIT also manufactures self-luminescent tritium filled sources.[4]
Krushak for mango irradiation - Building
BRIT profile
The application of radioisotopes in healthcare, industry, agriculture and research is one of the most wide-spread peaceful uses of the nuclear sciences, next to nuclear power production. Realizing the importance of the use of the radioisotopes for social benefits and national development, the Department of Atomic Energy has over the years, built up adequate infrastructure facilities for the production and applications of radioisotopes. Radioisotopes produced in the research reactor Dhurva at BARC. Trombay are formulated into a variety of radiochemicals, radiopharmaceuticals, sealed sources, radiation sources, labelled compounds and other allied products in the laboratories of BRIT and supplied to nearly 2000 institutions for use in medicine, industry, agriculture and supporting research in life sciences and bio-sciences.
Iodine - 131 Capsule FacilityMolybdenum-99 Production Facility at BRIT Vashi
In the health care sector, radioisotopes have contributed significantly to the development of new methods for diagnosis of diseases and cancer treatment using primarily sealed sources of 60Co. A number of Radioimmunoassay (RIA) kits are produced and supplied to a large number of hospitals and RIA laboratories all over the country. Radiochemicals, reference sources, labelled fertilizers, 14C as well as 3H labelled compounds are supplied by BRIT to many research laboratories, universities, educational institutions and agricultural institutions. BRIT also supplies 32P and 33P labelled nucleotides as well as 35S labelled methionine and cysteine products for use in molecular biology research.
High intensity 60Co teletherapy sources and brachytherapy sources of 192Ir and 137Cs for cancer therapy and Blood irradiators for irradiation of cellular blood components to reduce the risk of Graft-Versus-Host Disease (GVHO) are supplied by BRIT to many hospitals.
Karknidon - Indigenous Brachytherapy Equipment developed by BRIT, DAE, India
Laboratory scale research irradiators called "Gamma Chambers" supplied by BRIT are very much useful for research studies on radiation chemistry, radiobiology, food preservation, mutation, breeding, radiation hygienization etc. The use of medical products sterilized by gamma radiation greatly helps to improve the quality of health care and BRIT has contributed significantly for the establishment of radiation technology as an economically viable and superior method for sterilization of medical disposables.
Model of Brachytherapy Machine - KarknidonSulphur-32 Production Facility at BRIT Vashi
Radiation hygienization of spices and other food products extends their shelf life, reduces microbial load and losses due to spoilage without affecting the appearance, colour, aroma and flavour. BRIT has set up state of the art radiation processing facility for the hygienization of spices and other related products at Vashi, Navi Mumbai. BRIT offers total solution to the technology needs of radiation processing plant including supply of kiloCuries of 60Co sources used in such plants.
Krushak Plant - BRIT
In the industrial sector, BRIT is supplying industrial gamma radiography equipment and 192Ir and 60Co radioisotope sources for use in NDT examination and quality control of industrial components.
Gamma Radiation Scanning of Process Columns - Residence Time Distribution Studies of Process Columns
BRIT along with BARC provides professional services for trouble shooting particularly in chemical industries and oil refineries.
Leakage detection using radioisotopes
BRIT so far had following Chief Executives so far:
Dr. S. Gangadharan April 1994 to July 31, 2000
Dr. N. Ramamoorthy August 1, 2000 to September 30, 2003
Shri. J. K. Ghosh October 1, 2003 to December 31, 2005
Dr. A. K. Kohli from January 1, 2006 onwards
Products and services offered by BRIT for health, industry, agriculture and research
Products
Radiopharmaceuticals
Products of 131I, 99mTc, 51Cr for various diagnostic and therapeutic procedures
RIA / IRMA Kits
Thyroid related hormones
Hormones of reproductive systems
Radiation Sources
Radiography 192Ir, 60Co
Teletherapy 60Co
Brachytherapy 192Ir, 137Cs
Nucleonic Gauges 137Cs, 60Co
Radiochemicals
82Br, 46Sc, 203Hg and many others
Labelled Compounds
14C, 3H, 36S - Compunds
32P / 33P - Nucleotides
Equipments
Radiography Camera
For NDT Services : QC Testing; Preventive and predictive maintenances
Radiation Processing Plants and Research Irradiators
For radiation processing services and research
Low Dose Irradiators
For irradiation of products including blood and blood products to prevent
T-GVHD in immuno deficient recipients of blood transfusion
Services
Radiation Processing Services
Medical product sterilization (ISOMED - Trombay, Mumbai)
Radiation processing of spices & other products at Vashi, Navi Mumbai
Radiation processing of Low Dose products like mango (KRUSHAK)
Electron beam processing of cables, Polyethylene O-ring, gem stones, etc. at ILU-6, Vashi, Navi Mumbai
Sealed Sources Technology Services
Gamma scanning of process columns
Blockage detection in burried pipelines
Computed tomography
Radio-tracer Services
Industrial process parameters optimization
Dredging in ports / harbours
Leakage detection in pipelines
Milestones
Year
Milestone/s
2014
Gujarat Agro Industrial Group's irradiator at Bavla, Gujarat is Commissioned
Impartial Agrotech Pvt. Ltd.'s Irradiator at Unnao UP is commissioned
3 MCi multipurpose Gamma irradiator, a joint venture of BRIT and SYMEC is commisoned at Colombo in Sri Lanka
Blood Irradiator for Tsetse Fly Eradication Project at Addis Ababa, Ethiopia, jointly built by BRIT and SYMEC is commissioned
Contract with Los Alamos National Laboratory, USA for repatriation of sources of US origin is completed
MoU signed with M/s Raghuvansh Agro Farms Ltd. for Irradiator at Indore, MP
Frequency of production and supply of 131I- MIBG (Diagnostic and therapeutic) and 153Sm-EDTMP radiopharmaceuiticals is enhanced
High Activity 131I capsule Production: 3 Ci/batch milestone achieved
A compact NMR facility for the analysis of organic ligands and dueterated solvents is commisioned at RPhP
GMP compliant cold storage facility for TCK products is commisioned
RIA laboratory is certified by ISO 9001:2008, ISO 13485:2012 and CE marking
Barcoding system run on trial basis for recycling and management of hardware of Coltech Generators
Door Delivery of Radiopharmaceuticals started at Regional Centre, Bengaluru.
2013
BRIT gets Industrial Excellence Award from INS for 2012
Radioanalytical laobartory inaugurated at RC Bengaluru
882 kCi of Co-60 supplied to NIPRO in a single order
MoU signed with Kumaka Industries for setting up of Radiation processing plant at Sanand in Gujarat Construction of 3 MCi multipurpose * Gamma irradiator completed at Colombo in Sri Lanka
High dose I-131 capsules and Lu-177 EDTMP were launched
99mTc cold kits for TRODAT, HYNICTOC and TETROFOSMIN were launched
Customer Relations Cell for Radiopharmaceuticals started at Vashi, Navi Mumbai
Door delivery of radiopharmaceuticals started at Regional Centre, Delhi
2012
Civil construction started for Fission Moly Plant Project
NIPRO Corporation irradiator at Pune-Satara road and M/s Hindustan Agro Co-Operative Ltd., Rahuri, Maharashtra were commissioned
3 new MoUs were signed with ISORAD Tech. at Chennai, M/s Divyakiran at Anand, Gujarat and M/s Radura Irradiators, Nashik, Maharashtra for setting up radiation processing plants
32P Samarium phosphate colloid for radiation synovectomy and therapeutic 131I-MIBG were launched
65 Ci Iridium-192 radiography device ROLI-2 is launched
Blood irradiators supplied to CMC Vellore, Rajiv Gandhi Cancer Insitute, New Delhi, Surat Raktadan Kendra, Surat and Apollo Hospital, Hyderabad
2011
Column Generator Production facility commissioned at Vashi
High dose rate Brachytherapy equipment prototype made
Type B(U) approval obtained for 65 Ci Ir-192 radiography exposure device Roli-II
MoU signed with MSAMB, Vashi and M.s MSV laboratories for setting up of Radiation Processing Plant at Kanakpur, Dist. Medinipur, West Bengal for alsetting up of radiation processing plant
GC-5000 exported to National Institute for R & D in Physics & Nuclear Engineering Bucharest, Romania.
2010
ISOMED & RPP Vashi get ISO22000 & EU certification. ISOMED also gets MHRA, UK certification
MoUs signed with Gujarat agro, NIPRO Corporation, CCCL and Aligned Industries for radiation processing plants at Bavla, Pune, Tuticorin and Daruhera respectively
GC-5000 supplied and commissioned at Institute of Nuclear Chemistry and Technology, Warsaw, Poland.
Innova Agri Bio Park irradiator at Mahur commissioned.
Atomic Energy Commission sanctions Fission Molybdenum plant to be set up at ISOMED complex.
BRIT's sales turnover crosses Rs. 50 crore.
Introduction of LH IRMA kits, and indigenous MIBI kit.
Peregrine contract manufacturing of radiolabelling monoclonal antibody completed
2009
BRIT is recognized as a research centre by Mangalore University
ISOMED and RPP, Vashi get ISO 9001:2000 certification
Production of cold kits started in class 100 clean room
Tripartite agreement signed between BRIT-BARC-MSAMB for service operation of KRUSHAK
Radioactive real time transport tracking system launched
2008
Radiation Processing plant by M/s Agrosurg Irradiators at Vasai and M/s Gamma Agro medical at Hyderabad were commissioned
300 tons of mango irradiated in PPP mode at KRUSHAK for export to USA.
Received contract from AERE, Bangladesh for refurbishment of their Irradiator at Dhaka jointly with private company
M/s Friends Ventures and M/s Gamma Tech for Radiation Processing Plants at Chennai and Kanyakumari, Tamilnadu respectively
20 sets of Gel Generator assemblies exported to Kazakhstan under IAEA TCP
20 Ci ROLI- 3 camera launched
2007
Export of Co-60 to Vinagama HCM City and GC-5000 to NRI, Dalat, Vietnam
Mango irradiation taken up for export to USA
Gamma scanning & radiotracer services started
18F-NaF launched from MCF, Parel
Around 250 Geltech generators for 99mTc produced and supplied to hospitals in India
2006
Radioactive material transport Test Facility commissioned at Automotive Research Association of India (ARAI), Pune.
Carbon-14 Urea capsules for H. Pylori diagnosis launched
Collaborated with M/s Peregrine Pharmaceuticals, USA for 131I labelling of tumor necrosis drug
Radiation Processing Plant by M/s Microtrol Sterilization, Bengaluru Commissioned
2005
M/s. A.V. Processors 1000 kCi Radiation Processing Plant built under MoU with BRIT, inaugurated on November 16, 2005 at Ambernath, near Mumbai commisioned.
M/s. Universal Medicap Ltd’s 1000 kCi Radiation Processing Plant built under MoU with BRIT, inaugurated on December 14, 2005 at Vadodara.
Supply and installation of 100 kCi C060 sources for Vinagamma Plant, Vietnam
2004
First Radiation Processing Plant in private sector by M/s Organic Green Foods Limited is commissioned at Kolkata
BRIT exported 350 kCi Cobalt-60 to M/s MDS Nordion, Canada
Approval obtained from Atomic Energy Regulatory Board to Install and Operate Radiation Processing Plant f or frozen marine products, etc
2002
Medical Cyclotron Facility inaugurated at Parel
2000
Panoramic Batch Irradiator in Bangladesh commissioned
Radiation Processing Plant at Vashi, Navi Mumbai commissioned
First Compact Blood Irradiator launched
1999
Radiopharmaceuticals handling facility in Syria Commissioned
