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6-CAT

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6-CAT
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
3D model (JSmol)
  • C1CC2=C(CC1N)C=CC(=C2)Cl
  • InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 checkY
  • Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N checkY
  (verify)

6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.[1][2] It is a rigid analogue of para-chloroamphetamine (PCA).[1]

According to Nichols et al.,[3] 6-CAT is a non-neurotoxic analog of PCA.

See also

References

  1. ^ a b Fuller RW; Perry KW; Baker JC; Molloy BB (November 1974). "6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats". Archives Internationales de Pharmacodynamie et de Thérapie. 212 (1): 141–53. PMID 4455127.
  2. ^ Fuller, RW; Wong, DT; Snoddy, HD; Bymaster, FP (1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats". Biochem. Pharmacol. 26 (1): 1, 333–1, 337. doi:10.1016/0006-2952(77)90094-6.
  3. ^ Johnson, M. P.; Frescas, S. P.; Oberlender, R.; Nichols, D. E. (1991). "Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: Similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)". Journal of Medicinal Chemistry. 34 (5): 1662–1668. doi:10.1021/jm00109a020. PMID 1674539.