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Clinical data
  • N (US)
Routes of
Oral, nasal, IV
Legal status
Legal status
CAS Number
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
Molar mass221.2524 g/mol g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
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Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC, βk-MDEA), is a recreational designer drug classified as an entactogen, stimulant, and psychedelic of the phenethylamine, amphetamine, and cathinone chemical classes. It is the β-keto analogue of MDEA ("Eve"). Ethylone has only a short history of human use and is reported to be less potent than its relative methylone.[citation needed] In the United States, it began to be found in cathinone products in late 2011.[1]

Very little data exists about the pharmacological properties, metabolism, and toxicity of ethylone, and although several ethylone-related deaths have been reported, but the cause of death was not due to ingestion of ethylone.[1]


Analysis of human and rat urine for the metabolites of bk-amphetamines suggested that ethylone was degraded in the following metabolic steps:[2]

  1. N-deethylation to the primary amine.
  2. Reduction of the keto moiety to the respective alcohol.

Legal Status[edit]

As of October 2015 Ethylone is a controlled substance in China.[3]

See also[edit]


  1. ^ a b Dayong Lee; Chris W. Chronister; Jennifer Hoyer; Bruce A. Goldberger (September 2015). "Ethylone-Related Deaths: Toxicological Findings". Journal of Analytical Toxicology. 39 (7): 567–571. doi:10.1093/jat/bkv053. PMID 26025164.
  2. ^ Meyer, Markus R; Jens Wilhelm; Frank T. Peters; Hans H. Maurer (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry". Analytical and Bioanalytical Chemistry. 397 (3): 1225–1233. doi:10.1007/s00216-010-3636-5. PMID 20333362.
  3. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.

External links[edit]