Clofedanol
 | This article's factual accuracy may be compromised due to out-of-date information. (November 2011) |
 | |
| Clinical data | |
|---|---|
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Routes of administration | Oral |
| ATC code | |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.011.219 |
| Chemical and physical data | |
| Formula | C17H20ClNO |
| Molar mass | 289.80 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
  (what is this?) (verify) | |
Clofedanol (INN) or chlophedianol (BAN) is a centrally acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.[1] It is marketed in Canada under the trade name Ulone. GM Pharmaceuticals owns the patents to 113 combinations with Chlophedianol and was the first company to launch the cough suppressant in the United States.[2]
Chlophedianol was approved for OTC status in 1987 by the FDA OTC monograph process[3] and its safety and efficacy data are limited.
Synthesis
See also
References
- ^ "Clofedanol" (in French). BIAM. 1998-07-24. Retrieved 2007-04-15.
- ^ "How Odes Mitchell Built a Pharmaceutical Empire". D Magazine. Retrieved 2020-11-25.
- ^ "Department of Health and Human Services. Food and Drug Administration. 21 CFR Parts 310, 341, and 369. Docket No. 76N-052T. Cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the0counter human use; final monograph for OTC antitussive drug products. Federal Register 1987;52(155):30042-57" (PDF). FDA.gov. 1987-08-12.
 | This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it. |