CM156

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CM156
Identifiers
  • 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione
PubChem CID
ChemSpider
Chemical and physical data
FormulaC21H31N3S2
Molar mass389.62 g/mol g·mol−1
3D model (JSmol)
  • c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4
  • InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
  • Key:FJGOTAJCEJCFEV-UHFFFAOYSA-N

CM156[1] is a piperazine based chemical compound with nanomolar affinity for both sigma receptor subtypes that has been shown to counteract the deleterious effects of administered cocaine.

See also

References

  1. ^ Xu, Y. T.; Kaushal, N.; Shaikh, J.; Wilson, L. L.; Mesangeau, C.; McCurdy, C. R.; Matsumoto, R. R. (2010). "A Novel Substituted Piperazine, CM156, Attenuates the Stimulant and Toxic Effects of Cocaine in Mice". Journal of Pharmacology and Experimental Therapeutics. 333 (2): 491–500. doi:10.1124/jpet.109.161398. ISSN 0022-3565. PMC 2872963. PMID 20100904.



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