Fibrinogen gamma chain

FGG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1DUG, 1FIB, 1FIC, 1FID, 1FZA, 1FZB, 1FZC, 1FZE, 1FZF, 1FZG, 1LT9, 1LTJ, 1N86, 1N8E, 1RE3, 1RE4, 1RF0, 1RF1, 2A45, 2FFD, 2FIB, 2H43, 2HLO, 2HOD, 2HPC, 2HWL, 2OYH, 2OYI, 2Q9I, 2VDO, 2VDP, 2VDQ, 2VDR, 2VR3, 2XNX, 2XNY, 2Y7L, 2Z4E, 3BVH, 3E1I, 3FIB, 3GHG, 3H32, 3HUS, 4B60
Identifiers
Aliases	FGG, fibrinogen gamma chain
External IDs	OMIM: 134850; MGI: 95526; HomoloGene: 429; GeneCards: FGG; OMA:FGG - orthologs
Gene location (Human) Chr. Chromosome 4 (human) Band 4q32.1 Start 154,604,134 bp End 154,612,967 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3 E3|3 36.94 cM Start 82,915,031 bp End 82,922,356 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver beta cell decidua testicle lower lobe of lung right adrenal gland left adrenal cortex gallbladder upper lobe of lung upper lobe of left lung Top expressed in left lobe of liver lacrimal gland human fetus yolk sac gallbladder fetal liver hematopoietic progenitor cell parotid gland abdominal wall sexually immature organism primitive streak More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-macromolecule adaptor activity structural molecule activity metal ion binding protein binding signaling receptor binding cell adhesion molecule binding protein homodimerization activity extracellular matrix structural constituent Cellular component cytoplasm platelet alpha granule blood microparticle plasma membrane fibrinogen complex extracellular region cell surface extracellular exosome platelet alpha granule lumen external side of plasma membrane extracellular space endoplasmic reticulum lumen collagen-containing extracellular matrix Biological process hemostasis negative regulation of endothelial cell apoptotic process positive regulation of peptide hormone secretion protein polymerization positive regulation of heterotypic cell-cell adhesion fibrinolysis platelet degranulation blood coagulation extracellular matrix organization protein secretion response to calcium ion positive regulation of substrate adhesion-dependent cell spreading negative regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of vasoconstriction positive regulation of protein secretion positive regulation of ERK1 and ERK2 cascade positive regulation of exocytosis blood coagulation, fibrin clot formation plasminogen activation cell-matrix adhesion platelet aggregation signal transduction platelet activation toll-like receptor signaling pathway platelet maturation cellular response to interleukin-1 cellular response to interleukin-6 negative regulation of platelet aggregation post-translational protein modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2266 99571 Ensembl ENSG00000171557 ENSMUSG00000033860 UniProt P02679 Q8VCM7 RefSeq (mRNA) NM_021870 NM_000509 NM_133862 NM_001317105 RefSeq (protein) NP_000500 NP_068656 NP_001304034 NP_598623 Location (UCSC) Chr 4: 154.6 – 154.61 Mb Chr 3: 82.92 – 82.92 Mb PubMed search
Wikidata
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Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4.