Radiation-induced lung injury
|Radiation-induced lung injury|
|Classification and external resources|
Radiation-induced lung injury is a general term for damage to the lungs which occurs as a result of exposure to ionizing radiation. In general terms, such damage is divided into early inflammatory damage (radiation pneumonitis) and later complications of chronic scarring (radiation fibrosis). Pulmonary radiation injury most commonly occurs as a result of radiation therapy administered to treat cancer.
Symptoms and signs
The lungs are a radiosensitive organ, and radiation pneumonitis can occur leading to pulmonary insufficiency and death (100% after exposure to 50 gray of radiation), in a few months. Radiation pneumonitis is characterized by:
- Marks, Lawrence B.; Yu, Xiaoli; Vujaskovic, Zjelko; Small, William; Folz, Rodney; Anscher, Mitchell S. (July 2003). "Radiation-induced lung injury". Seminars in Radiation Oncology. 13 (3): 333–345. doi:10.1016/S1053-4296(03)00034-1. ISSN 1053-4296. PMID 12903021. – via ScienceDirect (Subscription may be required or content may be available in libraries.)
- Radiation Emergancy Medical Management. "Time Phases of Acute Radiation Syndrome - Radiation Emergency Medical Management". www.remm.nlm.gov. U.S. Department of Health and Human Services. Retrieved 7 November 2017.