Nervonic acid
Appearance
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Names | |
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IUPAC name
(Z)-Tetracos-15-enoic acid
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Other names
cis-15-Tetracosenoic acid
24:1 cis, delta 9 or 24:1 omega 9 | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.108.655 |
KEGG | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C24H46O2 | |
Molar mass | 366.62 g/mol |
Melting point | 42–43 °C |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Nervonic acid is a monounsaturated omega-9 fatty acid. Nervonic acid has been identified as important in the biosynthesis of nerve cell myelin.[2] It is found in the sphingolipids of white matter in human brain.
Nervonic acid is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.[3]
Notes
- ^ Nervonic acid at Sigma-Aldrich
- ^ US Patent 6664406, Nervonic acid derivatives, their preparation and use
- ^ WO/1996/005740, Nervonic Acid Compositions
Additional references
- Appelqvist (1976) Lipids in Cruciferae. In: Vaughan JG, Macleod AJ (Eds), The biology and the Chemistry of Cruciferae. Academic Press, London, UK, pp. 221-277.
- Sargent JR, Coupland K, Wilson R (1994). Nervonic Acid and Demyelinating Disease. Medical Hypothesese 42, pp. 237-242.