C8:0 (Lipid numbers)
|Jmol interactive 3D||Image|
|Molar mass||144.21 g/mol|
|Appearance||Oily colorless liquid|
|Odor||faint, fruity-acid; irritating|
|Melting point||16.7 °C (62.1 °F; 289.8 K)|
|Boiling point||239.7 °C (463.5 °F; 512.8 K)|
|0.068 g/100 mL|
|Solubility||soluble in alcohol, chloroform, ether, CS2, petroleum ether, acetonitrile|
|Vapor pressure||0.25 Pa|
Refractive index (nD)
|297.9 J/K mol|
Std enthalpy of
|Flash point||130 °C (266 °F; 403 K)|
|440 °C (824 °F; 713 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|10.08 g/kg (orally in rats)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Caprylic acid is the common name for the eight-carbon saturated fatty acid known by the systematic name octanoic acid. Its compounds are found naturally in the milk of various mammals, and as a minor constituent of coconut oil and palm kernel oil. It is an oily liquid that is minimally soluble in water with a slightly unpleasant rancid-like smell and taste.
Caprylic acid is used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
It has been observed that Malonyl-CoA inhibits palmitic acid oxidation in isolated mitochondria, but that it has little or no effect on the oxidation of octanoic acid (C8, Saturated). This observation can be explained by AMP functions serving as an energy sensor and regulator of metabolism. When ATP production does not keep up with needs, a higher portion of a cell's adenine nucleotide pool is in the form of AMP. AMP promotes catabolic pathways that lead to synthesis of ATP, while inhibiting energy-utilizing synthetic pathways. For example, AMP regulates fatty acid synthesis and catabolism by controlling availability of malonyl-CoA.
Caprylic acid is an antimicrobial pesticide used as a food contact surface sanitizer in commercial food handling establishments on dairy equipment, food processing equipment, breweries, wineries, and beverage processing plants. It is also used as disinfectant in health care facilities, schools/colleges, animal care/veterinary facilities, industrial facilities, office buildings, recreational facilities, retail and wholesale establishments, livestock premises, restaurants, and hotels/motels. In addition, caprylic acid is used as an algaecide, bactericide, and fungicide in nurseries, greenhouses, garden centers, and interiorscapes on ornamentals. Products containing caprylic acid are formulated as soluble concentrate/liquids and ready-to-use liquids.
For ghrelin to have a hunger-stimulating action on a hypothalamus, caprylic acid must be linked to a serine residue at the 3-position of ghrelin. To cause hunger, it must acylate an -OH group. Other fatty acids in the same position have similar effects on hunger.
Caprylic acid is taken as a dietary supplement.
Some studies have shown that medium-chain triglycerides (MCTs) can help in the process of excess calorie burning, and thus weight loss. MCTs are also seen as promoting fat oxidation and reduced food intake. There has also been interest in MCTs from endurance athletes and the bodybuilding community.
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- at 2.06–2.63 K
- at −191 °C
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