Rubidium-82 chloride
| Names | |
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| IUPAC name
Rubidium-82 chloride
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| Systematic IUPAC name
(82Rb)Rubidium chloride | |
| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
| KEGG | |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| ClRb | |
| Molar mass | 117.371 g mol−1 |
| Pharmacology | |
| V09GX04 (WHO) | |
| Related compounds | |
Other cations
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Caesium chloride Lithium chloride |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Rubidium-82 chloride is a form of rubidium chloride using a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 (Bracco Diagnostics) in the use of Myocardial perfusion imaging (imaging of the heart).[1] It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging.[2] The half-life of the rubidium-82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.[3]
References
- ^ Th Wackers, Frans J; Bruni, Wendy; Zaret, Barry L (2007-11-19). "Rubidium-82 Generator". Nuclear cardiology: the basics : how to set up and maintain a laboratory. ISBN 978-1-58829-924-6.
- ^ Ballinger, James R. (2009). "Integrating Cardiology for Nuclear Medicine Physicians": 379–385. doi:10.1007/978-3-540-78674-0_32. ISBN 978-3-540-78673-3.
{{cite journal}}:|chapter=ignored (help); Cite journal requires|journal=(help) - ^ K. L. Gould et al. "Clinical feasibility of positron cardiac imaging without a cyclotron using generator-produced rubidium-82." Journal of the American College of Cardiology 1986;7:775-789. [1]
Further reading
- Clarke, Michael J; Sadler, P. J (1999-06-15). Metallopharmaceuticals: Diagnosis and therapy. ISBN 978-3-540-65308-0. (Note: only about 1/2 page on Rb-generator)
- Alvarez-Diez, T; Dekemp, R; Beanlands, R; Vincent, J (1999). "Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomography". Applied Radiation and Isotopes. 50 (6): 1015–23. doi:10.1016/S0969-8043(98)00170-5. PMID 10355104.
- Waters, S. L.; Curseys, B. M., eds. (1987). "The Strontium-82/rubidium-82 generator". International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes. 38 (3): 171–239.
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