Jump to content

Salicylaldehyde dehydrogenase

From Wikipedia, the free encyclopedia
salicylaldehyde dehydrogenase
Identifiers
EC no.1.2.1.65
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a salicylaldehyde dehydrogenase (EC 1.2.1.65) is an enzyme that catalyzes the chemical reaction

salicylaldehyde + NAD+ + H2O salicylate + NADH + 2 H+

The 3 substrates of this enzyme are salicylaldehyde, NAD+, and H2O, whereas its 3 products are salicylate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is salicylaldehyde:NAD+ oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.

References

[edit]
  • Eaton RW, Chapman PJ (1992). "Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions". J. Bacteriol. 174 (23): 7542–54. PMC 207464. PMID 1447127.