Small nuclear ribonucleoprotein polypeptide A

SNRPA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AUD, 1DRZ, 1DZ5, 1FHT, 1M5K, 1M5O, 1M5P, 1M5V, 1NU4, 1OIA, 1SJ3, 1SJ4, 1SJF, 1U6B, 1URN, 1VBX, 1VBY, 1VBZ, 1VC0, 1VC5, 1VC6, 1ZZN, 2A3J, 2NZ4, 2OIH, 2OJ3, 2U1A, 3BO2, 3BO3, 3BO4, 3CUL, 3CUN, 3EGZ, 3G8S, 3G8T, 3G96, 3G9C, 3HHN, 3IIN, 3IRW, 3IWN, 3K0J, 3L3C, 3MUM, 3MUR, 3MUT, 3MUV, 3MXH, 3P49, 3PGW, 3R1H, 3R1L, 3UCU, 3UCZ, 3UD3, 3UD4, 4C4W, 4PR6, 4PRF, 4W90, 4YB1, 5DDO, 5DDR, 5DDQ, 5DDP, 5FJ4
Identifiers
Aliases	SNRPA, Mud1, U1-A, U1A, Small nuclear ribonucleoprotein polypeptide A
External IDs	OMIM: 182285; MGI: 1855690; HomoloGene: 3380; GeneCards: SNRPA; OMA:SNRPA - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	40,765,389 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	26,895,696 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; mucosa of transverse colon; ; left ovary; ; ventricular zone; ; canal of the cervix; ; right ovary; ; body of uterus; ; right lobe of thyroid gland; ; popliteal artery; ; tibial arteries;
	Top expressed in
	epiblast; ; yolk sac; ; ventricular zone; ; tail of embryo; ; neural tube; ; genital tubercle; ; ganglionic eminence; ; embryo; ; embryo; ; mesencephalon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	U1 snRNA binding; snRNA stem-loop binding; protein binding; RNA binding; nucleic acid binding; U1 snRNP binding; identical protein binding;
Cellular component	spliceosomal complex; nucleus; nucleoplasm; U1 snRNP;
Biological process	mRNA processing; regulation of mRNA polyadenylation; RNA splicing; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	6626
	53607
	ENSG00000077312
	ENSMUSG00000061479
	P09012
	Q62189
	NM_004596
	NM_001046637; NM_001285825; NM_015782
	NP_004587
	NP_001040102; NP_001272754; NP_056597
	Wikidata
View/Edit Human	View/Edit Mouse

U1 small nuclear ribonucleoprotein A is a protein that in humans is encoded by the SNRPA gene.^[5]^[6]

Template:PBB Summary

Interactions

Small nuclear ribonucleoprotein polypeptide A has been shown to interact with CDC5L.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000077312 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061479 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schonk D, van Dijk P, Riegmann P, Trapman J, Holm C, Willcocks TC, Sillekens P, van Venrooij W, Wimmer E, Geurts van Kessel A, et al. (January 1991). "Assignment of seven genes to distinct intervals on the midportion of human chromosome 19q surrounding the myotonic dystrophy gene region". Cytogenet Cell Genet. 54 (1–2): 15–9. doi:10.1159/000132946. PMID 1701111.
^ "Entrez Gene: SNRPA small nuclear ribonucleoprotein polypeptide A".
^ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23). ENGLAND: 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

v t e RNA-binding protein: Ribonucleoproteins
snRNP	A A1 B B2 C D1 D2 D3 E F G N 70K/U1 spliceosomal RNA SNRNP200
hnRNP	A0 C L R
Other transcription	Telomerase
Translation	Ribosome
Vault ribonucleoprotein particles	Major vault protein
Other	Signal recognition particle

Interactions

References

Further reading