Transcellular fluid

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Transcellular fluid is the portion of total body water that represents all body fluids which are formed from the transport activities of cells. It is the smallest component of extracellular fluid. It is contained within epithelial lined spaces. It is often not calculated as a fraction of the extracellular fluid, but it is 5% of extracellular fluid (2.5% of total body water). Examples of this fluid are cerebrospinal fluid, ocular fluid and joint fluid.[1][2]


Due to the varying locations of transcellular fluid, the composition changes dramatically. Some of the electrolytes present in the transcellular fluid are sodium ions, chloride ions, and bicarbonate ions.

Physiological Function[edit]

There are also varied functions for the trans-cellular fluid. In the joints, it serves a lubrication function, while the urine allows for the removal of electrolytes and molecules from the body.


  1. ^ Fluid Physiology: 2.1 Fluid Compartments
  2. ^ Constanzo, Linda S. (2014). Physiology, 5th Ed. Elsevier Saunders. p. 264. ISBN 9781455708475.

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