Zinc finger protein 180

ZNF180
Identifiers
Aliases	ZNF180, HHZ168, zinc finger protein 180
External IDs	OMIM: 606740; MGI: 1923701; HomoloGene: 8306; GeneCards: ZNF180; OMA:ZNF180 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	44,500,524 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	23,807,138 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; testicle; ; gonad; ; Achilles tendon; ; ganglionic eminence; ; ventricular zone; ; granulocyte; ; islet of Langerhans; ; sural nerve; ; parietal pleura;
	Top expressed in
	hand; ; olfactory tubercle; ; superior cervical ganglion; ; primary motor cortex; ; Region I of hippocampus proper; ; Rostral migratory stream; ; lobe of cerebellum; ; superior frontal gyrus; ; nucleus accumbens; ; cingulate gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7733
	210135
	ENSG00000167384
	ENSMUSG00000057101
	Q9UJW8
	n/a
NM_001278508; NM_001278509; NM_001288759; NM_001288760; NM_001288761;
	NM_001288762; NM_001291633; NM_013256
NM_001045486; NM_001289634; NM_001289637; NM_001289640; NM_001289641;
	NM_172483
NP_001265437; NP_001265438; NP_001275688; NP_001275689; NP_001275690;
	NP_001275691; NP_001278562; NP_037388
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 180 is a protein that is encoded in humans by the ZNF180 gene. ^[5]

Function

Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing two specifically positioned cysteines and two histidines that are involved in coordinating zinc. Kruppel-related proteins form one family of zinc finger proteins. See MIM 604749 for additional information on zinc finger proteins.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167384 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000057101 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger protein 180". Retrieved 2016-01-29.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167384 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000057101 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Zinc finger protein 180". Retrieved 2016-01-29.

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